Biotage AB and McMaster University sign two year extension to Molecular Imaging Development Agreement

06-Mar-2008

Biotage AB and McMaster University sign a two year extension to molecular imaging Development Agreement. McMaster University has successfully completed the first year research agreement, with a key journal publication and several technical presentations.

"We used the Biotage Initiator Microwave synthesis system, chromatography cartridges to prepare a range of Carborane Cage structures labeled with rhenium and technetium (Tc99c), the currently most used radionuclide in diagnostic medicine. We reported an 85% reduction in synthesis time and 26% gain in decay corrected yield, when compared to the traditional synthesis methods. The speed, purity and flexibility of this approach will drive the development of a new generation of novel molecular imaging agents." Dr. John F. Valliant, Associate Professor of Chemistry and Medical Physics and Acting Director of McMaster Institute of Applied Radiation Sciences (McIARS) stated.

Based on the success of this first phase, both parties have agreed to a 2-year extension of the work at McMaster. Valliant reports, "The next research phase will expand microwave synthesis to a broader range of radionuclides and probes used in the PET imaging and as therapeutic agents."

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