Bio-Rad Laboratories
RNA Therapeutics: Ultrasensitive detection and absolute quantification with Droplet Digital PCR
Bio-Rad Laboratories Ltd.
Transforming Bioanalysis of RNA Therapeutics, from Discovery and Development to Manufacturing QC
Advances in therapeutic RNAs have exploded in recent years. These novel drugs have the potential to make personalized medicine a reality and, at the same time, make the term “undruggable” obsolete. Therapeutic RNAs can be used to provide a sequence-specific modulation of gene expression to cause a desired biological response with a beneficial health outcome. Collectively, RNA therapeutics consist of multiple types of RNAs that include small activating RNAs (saRNA), antisense oligonucleotides (ASO), microRNAs (miRNA), small interfering RNAs (siRNA), and messenger RNAs (mRNA). ddPCR technology has proven to be an invaluable analytical asset and is extensively used at various stages of the RNA development and production process to support the development and production of safe and effective RNA-based therapeutics.
White Paper classification
White papers on related topics
Products on related topics
You may also be interested in these white papers
See the theme worlds for related content
Topic World Cell Analysis
Cell analyse advanced method allows us to explore and understand cells in their many facets. From single cell analysis to flow cytometry and imaging technology, cell analysis provides us with valuable insights into the structure, function and interaction of cells. Whether in medicine, biological research or pharmacology, cell analysis is revolutionizing our understanding of disease, development and treatment options.
Topic World Cell Analysis
Cell analyse advanced method allows us to explore and understand cells in their many facets. From single cell analysis to flow cytometry and imaging technology, cell analysis provides us with valuable insights into the structure, function and interaction of cells. Whether in medicine, biological research or pharmacology, cell analysis is revolutionizing our understanding of disease, development and treatment options.
Topic World PCR
This groundbreaking and highly versatile molecular technique of PCR allows us to amplify tiny amounts of genetic material on a large scale and analyze them in detail. Whether in medical diagnostics, forensic DNA analysis or research into genetic diseases - PCR is an indispensable tool that gives us deep insights into the world of DNA. Immerse yourself in the fascinating world of the polymerase chain reaction (PCR)!
Topic World PCR
This groundbreaking and highly versatile molecular technique of PCR allows us to amplify tiny amounts of genetic material on a large scale and analyze them in detail. Whether in medical diagnostics, forensic DNA analysis or research into genetic diseases - PCR is an indispensable tool that gives us deep insights into the world of DNA. Immerse yourself in the fascinating world of the polymerase chain reaction (PCR)!
Last viewed contents
High throughput phenotyping of uropathogenic E. coli isolates with Fourier transform infrared spectroscopy
How to count the messenger out - Mapping the structure of protonated water clusters
Fair Rules for Sharing Sequence Data: New roadmap in Nature Microbiology - Combining openness and fairness in the data-intensive life sciences
A new addition to the CRISPR toolbox: Teaching the gene scissors to detect RNA - Researchers present the PUMA technology for the precise detection of RNA with DNA-cutting Cas12 nucleases
New deep learning algorithm can pick up genetic mutations and DNA mismatch repair deficiency in colorectal cancers more efficiently - The findings open up the possibility to select patients likely to benefit from targeted therapies at lower costs and with quicker turnaround times as compared to current methods
Sartorius Grows by Double Digits - Targets for 2020 Updated
First-ever blueprint of a minimal cell is more complex than expected - EMBL and CRG scientists reveal what a self-sufficient cell can't do without
Scientists realize quantum simulation of the Unruh effect
Highest-resolution view of subcellular, single-molecule, spatial biology - Resolve Biosciences Secures $71 Million Series B Financing
New method developed for investigating the internal structure of atoms - Previously unknown properties of the element samarium revealed
Opening the Way to Mobile Olfaction with Nanomechanical Sensors
