Thrombosis - 6 News
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Specific control molecule in platelets identified
Starting point for drug development against thrombosis, heart attack and stroke
12-Aug-2020 - The previously largely unknown molecule bridging integrator 2 (BIN2) plays a central role in platelet activation, as researchers from Würzburg have now shown in a joint project of the DFG Collaborative Research Centre/Transregio 240. This finding provides indications of starting points for drug ...
Multiple roles of glucose metabolism in platelet activation and survival identified
07-Aug-2017 - Platelets, the cells in blood that enable clotting, are highly reliant on their ability to metabolize glucose, according to a new study by researchers at the University of Iowa. The findings may have implications for understanding the increased risk of thrombosis--blood clots inside blood ...
Detecting blood clot risk using biomarkers
17-Mar-2017 - Cancer is one of the hardest medical conditions to overcome, and for those who do so, the battle often does not stop at remission. Many cancers predispose patients to develop blood clots, particularly patients who are diagnosed at a late stage, which often complicates their treatment and reduces ...
Greater Accuracy in Gauging Blood Coagulation
Fluorogenic Peptide-Based Substrates for Monitoring Thrombin Activity
24-Feb-2012 - Thrombin plays a key role in various pathologies of the haemostatic system. Overexpression of thrombin can result in thrombosis, whereas its underexpression might lead to haemophilia. Therefore, accurate monitoring of thrombin activity is crucial for determining the proper treatment of a given ...
Plastic biochip speeds up protein detection
Using fluorescent polymers to quickly detect attomoles of protein
10-Oct-2006 - A new, fast, and inexpensive way to test for medically important molecules, such the blood clot protein thrombin and faulty proteins present in Alzheimer's disease, could emerge from research published in the journal Advanced Materials. Mario Leclerc and his colleagues at Université Laval in ...
Celera and Collaborators Discover Genetic Markers Associated with Early-onset Heart Attacks
15-May-2006 - Celera Genomics, an Applera Corporation business, the University of California, San Francisco (UCSF), Cleveland Clinic, Case Western Reserve University and Brigham Young University, announced a publication describing two novel genetic markers associated with an increased risk for myocardial ...
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