Proteome analysis - 10 News

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Proteome analysis - 10 News

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First ​“protein map” of neurons that initiate pain reveals new targets for drugs

Deep Visual Proteomics applied to nerve cells for the first time

15-Apr-2026 - One in five people worldwide suffers from chronic inflammatory pain. Meanwhile, about two thirds of those affected find little relief from existing pain medications; new therapeutic approaches are urgently needed. ​“We first must understand precisely how sensory nerve cells trigger pain at the ...

proteome analysis artificial intelligence chronic inflammatory diseases
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Systematic depiction of previously unknown gene functions

Largest cellular proteomic study of yeast cells unlocks fundamental insights

03-May-2023 - A proteome is the entirety of all active protein molecules present within an organism, a certain type of tissue, or a cell under specific conditions and at a certain time. Now, an international team of researchers led by members from Charité – Universitätsmedizin Berlin, the Francis Crick ...

proteome analysis genes mass spectrometry
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Novel spatial-omics technology enables investigation of diseases at their early stages

How can you trace a single diseased cell in an intact brain or a human heart?

28-Dec-2022 - The search resembles looking for a needle in a haystack. The teams of Ali Ertürk at Helmholtz Munich and LMU Munich and Matthias Mann at the Max Planck Institute of Biochemistry in Martinsried near Munich have now developed a new technology named DISCO-MS that solves the problem. DISCO-MS uses ...

proteome analysis early diagnosis mass spectrometry
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Mass spectrometry-based draft of the mouse proteome

A milestone for biomedical research

30-Jun-2022 - Proteins control and organize almost every aspect of life. The totality of all proteins in a living organism, a tissue or a cell is called the proteome. Using mass spectrometry, researchers at the Technical University of Munich (TUM) characterize the proteome, or protein complement of the genome, ...

proteome analysis mass spectrometry proteins
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MaxDIA – taking proteomics to the next level

Highly sensitive and accurate data analysis: New software improves data-independent acquisition proteomics

12-Jul-2021 - Proteomics produces enormous amounts of data, which can be very complex to analyze and interpret. The free software platform MaxQuant has proven to be invaluable for data analysis of shotgun proteomics over the past decade. Now, Jürgen Cox, group leader at the Max Planck Institute of ...

proteome analysis data analysis machine learning
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Could the blood of COVID-19 patients be used to predict disease progression?

Study discovers differences in the blood samples of severe and mild cases

09-Jun-2020 - Researchers from Charité – Universitätsmedizin Berlin and the Francis Crick Institute have identified 27 proteins which are present at different levels in the blood of COVID-19 patients, depending on the severity of their symptoms. These biomarker profiles could be used to predict disease ...

proteome analysis biomarkers blood
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A molecular map for the plant sciences

First comprehensive map of the proteome of the model plant Arabidopsis thaliana

16-Mar-2020 - Plants are essential for life on earth. They provide food for essentially all organisms, oxygen for breathing, and they regulate the climate of the planet. Proteins play a key role in controlling all aspects of life including plants. Under the leadership of the Technical University of Munich ...

proteome analysis Arabidopsis thaliana databases
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Otto Hahn Medal for Sanja Sviben

Award for research of biomineralization in coccolithophorid algae

12-Jun-2018 - Sanja Sviben has been awarded with the Otto Hahn Medal from the Max Planck Society (MPG). She will receive the award during the annual meeting of the MPG, which takes place from June 13th-14th in Heidelberg. The society recognizes her outstanding doctoral thesis on the investigation of the ...

proteome analysis biomaterials biomineralization
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Milestone for the analysis of human proteomes

Synthetic peptides and spectra for proteomics

01-Feb-2017 - Researchers led by the Technical University of Munich (TUM) report on the synthesis of a library of more than 330,000 reference peptides representing essentially all canonical proteins of the human proteome. It is a major milestone in the ProteomeTools project which aims at translating human ...

proteome analysis compound libraries LC/MS-MS coupling

Worldwide standards for clinical proteome analyses

The dream of individual medicine gets the scientific basis

01-Mar-2007 - After the many pitfalls of the GENOMICS-era, the basis for worldwide standards for clinical proteome research aiming towards early detection of live-threatening diseases as well as evaluation of therapeutic success has been set. With the publication of suggested guidelines in PROTEOMICS - ...

proteome analysis bladder cancer clinical trials
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