13 Current news of MDC

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Towards a cell-based interceptive medicine in Europe

Diagnose diseases earlier and intercept disorders before irreparable damage occurs

09-Sep-2020

Hundreds of researchers, clinicians, industry leaders and policy makers from all around Europe are united by a vision of how to revolutionize healthcare. In a perspective in Nature and the LifeTime Strategic Research Agenda they now present a roadmap of how to leverage the latest scientific ...

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Diagnostics, meet CRISPR

15-Apr-2020

A new diagnostic test to quickly and easily monitor kidney transplant patients for infection and rejection relies on a simple urine sample and a powerful partner: the gene-editing technology CRISPR. Michael Kaminski, who developed it, leads a new Emmy Noether Group at the MDC & Charité. The ...

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On the trail of cancer stem cells

What goes on inside and between individual cells during the very earliest stages of tumor development?

24-Feb-2020

Single cell sequencing technologies and a mouse model have enabled researchers to comprehensively map the cellular diversity of whole salivary gland tumors and trace the path of cancer stem cells. Two research teams from the Max Delbrück Center for Molecular Medicine and their collaborators have ...

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Tracking titin in real time

17-Dec-2019

Using new high-resolution imaging techniques, MDC researchers and colleagues have tracked titin, the body’s largest protein, in real time throughout its entire lifecycle. The method and results could provide new insight into muscle development as well as treating damaged muscles and heart ...

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FLAM-seq: the full picture of messenger RNA and their tails

19-Aug-2019

Researchers in MDC’sBerlin Institute for Medical Systems Biology(BIMSB)have developed atoolenablingaccurate sequencing ofmessenger RNA along withtheirtails for the first time.ProfessorNikolausRajewskyand his team described this new tool, called full-length poly(A) and mRNA ...

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Google Maps for tissues

08-Aug-2019

Modern light microscopic techniques provide extremely detailed insights into organs, but the terabytes of data they produce are usually nearly impossible to process. New software, developed by a team led by MDC scientist Dr. Stephan Preibisch and now presented in Nature Methods, is helping ...

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Keeping a cell’s powerhouse in shape

12-Jul-2019

A German-Swiss team around Professor Oliver Daumke from the MDC has investigated how a protein of the dynamin family deforms the inner mitochondrial membrane. Mitochondria are the powerhouses of our cells, generating energy in the form of chemical compounds such as ATP. To do this job ...

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Decoding Lil BUB: Crowdfunded project reveals genome of internet celebrity cat

06-Mar-2019

Lil BUB has drawn millions of followers across the internet for her cute appearance. Behind the celebrity cat’s unique features is a combination of two rare genetic variants, three molecular biologists from Germany and the US report. The results of their crowdfunded project “LilBUBome” are now ...

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Transplanted hearts reveals risk gene for cardiovascular disease

14-Sep-2017

In the largest transcriptome study to date, an international research team analysed the RNA of transplanted hearts and discovered a number of new risk factors for dilated cardiomyopathy and other heart conditions which could thus be recognised more easily in future. We know of many genes with ...

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How proteins reshape cell membranes

27-Feb-2017

Small "bubbles" frequently form on membranes of cells and are taken up into their interior. The process involves EHD proteins - a focus of research by Prof. Oliver Daumke of the MDC. He and his team have now shed light on how these proteins assemble on the surface of a cell and reshape its ...

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