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Tracking titin in real time

17-Dec-2019

Using new high-resolution imaging techniques, MDC researchers and colleagues have tracked titin, the body’s largest protein, in real time throughout its entire lifecycle. The method and results could provide new insight into muscle development as well as treating damaged muscles and heart ...

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FLAM-seq: the full picture of messenger RNA and their tails

19-Aug-2019

Researchers in MDC’sBerlin Institute for Medical Systems Biology(BIMSB)have developed atoolenablingaccurate sequencing ofmessenger RNA along withtheirtails for the first time.ProfessorNikolausRajewskyand his team described this new tool, called full-length poly(A) and mRNA ...

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Google Maps for tissues

08-Aug-2019

Modern light microscopic techniques provide extremely detailed insights into organs, but the terabytes of data they produce are usually nearly impossible to process. New software, developed by a team led by MDC scientist Dr. Stephan Preibisch and now presented in Nature Methods, is helping ...

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Keeping a cell’s powerhouse in shape

12-Jul-2019

A German-Swiss team around Professor Oliver Daumke from the MDC has investigated how a protein of the dynamin family deforms the inner mitochondrial membrane. Mitochondria are the powerhouses of our cells, generating energy in the form of chemical compounds such as ATP. To do this job ...

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Decoding Lil BUB: Crowdfunded project reveals genome of internet celebrity cat

06-Mar-2019

Lil BUB has drawn millions of followers across the internet for her cute appearance. Behind the celebrity cat’s unique features is a combination of two rare genetic variants, three molecular biologists from Germany and the US report. The results of their crowdfunded project “LilBUBome” are now ...

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Transplanted hearts reveals risk gene for cardiovascular disease

14-Sep-2017

In the largest transcriptome study to date, an international research team analysed the RNA of transplanted hearts and discovered a number of new risk factors for dilated cardiomyopathy and other heart conditions which could thus be recognised more easily in future. We know of many genes with ...

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How proteins reshape cell membranes

27-Feb-2017

Small "bubbles" frequently form on membranes of cells and are taken up into their interior. The process involves EHD proteins - a focus of research by Prof. Oliver Daumke of the MDC. He and his team have now shed light on how these proteins assemble on the surface of a cell and reshape its ...

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Analytica Research Prize for Dr. Matthias Selbach of MDC

New Method for Measuring the Production of Thousands of Proteins

31-Mar-2010

Dr. Matthias Selbach, biologist at the Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch, Germany, has been honored with the Analytica Research Prize 2010 in an award ceremony at the Analytica 2010 trade fair in Munich. Dr. Selbach received the prize, which is endowed with 25 000 ...

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New Mechanism for Cardiac Arrhythmia discovered

01-Oct-2008

It has long been thought that virus infections can cause cardiac arrhythmia. But why has not been understood. Ulrike Lisewski, Dr. Yu Shi, Michael Radke and Professor Michael Gotthardt of the Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch, Germany, have now discovered the molecular ...

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Camouflage mechanism of cancer cells in Hodgkin's lymphoma decoded

Curt Meyer Memorial Prize for Dr. Stephan Mathas and Dr. Martin Janz

08-Jul-2008

Cancer researchers Dr. Martin Janz and Dr. Stephan Mathas of the Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch and the Charité - University Medicine Berlin, Germany, have been honored with the Curt Meyer Memorial Prize for their research on Hodgkin's lymphoma. They received the ...

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