Microscopy - 9 News by Uni Freiburg
Research team reveals hidden particle interactions at the cell surface
Ultra-smooth interactions can be detected through high-speed measurement and frequency analysis
18-Jul-2023 - Is it possible that in most measurements in the field of life sciences, important interactions remain hidden inside the cell or at the cell surface? This question has puzzled the team of laser- and bio-physicist Prof. Dr. Alexander Rohrbach from the University of Freiburg for years. He and his ...
Cytoskeleton acts as cells’ bouncer for bacteria
Researchers have discovered a previously unknown function of septins in defending cells against dangerous hospital pathogens
24-Oct-2022 - Pseudomonas aeruginosa (P.a.) are resistant to most antibiotics and cause life-threatening infections of wounds or the lungs. The P.a. bacteria species has an entire arsenal of strategies for evading the immune system and infecting tissue. Researchers working with Prof. Dr. Winfried Römer and Dr. ...
Molecular structure of one of the most important receptors in the immune system unraveled
Researchers publish the three-dimensional structure of the B cell antigen receptor, shedding new light on its composition
21-Oct-2022 - The surface of B cells is covered with antigen receptors with which they recognize invading pathogens such as bacteria and viruses. When a B cell receptor binds to an antigen, that is, to a foreign structure, the B cell is activated and triggers the production of antibodies. Antibodies are ...
Rotating blue laser light reveals unimagined dynamics in living cells
Using a novel laser-scanning microscope scientists observe processes in cells changing within milliseconds
19-Apr-2022 - When cities transform into a colorful world of lights as darkness falls, it’s often only possible to estimate their contours, which depending on the perspective can draw the attention to key details or trivia. In fluorescence microscopy, biological cells are marked with fluorescent dyes and ...
Measuring the Nanoworld
Researchers establish a benchmark for accurate determination of internal dimensions within individual molecules
05-Sep-2018 - A worldwide study involving 20 laboratories has established and standardized a method to measure exact distances within individual biomolecules, down to the scale of one millionth of the width of a human hair. The new method represents a major improvement of a technology called single-molecule ...
Evolution of Cellular Power Stations
The protein OXA plays an important role in integrating protein molecules into mitochondria
19-May-2016 - Mitochondria are the power stations of human cells. They provide the energy needed for the cellular metabolism. But how did these power stations evolve, and how are they constructed? Researchers from the University of Freiburg studied the role of so-called oxidase assembly machinery, or OXA, in ...
Soft Probing with Optical Tweezers
Researchers have developed a method for measuring soft, structured surfaces using optical forces
13-Oct-2015 - Surfaces separate outside from inside, control chemical reactions, and regulate the exchange of light, heat, and moisture. They thus play a special role in nature and technology. In the journal Nature Nanotechnology, the Freiburg physicist Prof. Dr. Alexander Rohrbach and his former PhD candidate ...
A new Concept in Microscopy: Self-reconstructing Laser Beams
Researchers at the University of Freiburg are developing a microscope with illuminating beams that actively refocus in a light-scattering medium
14-Oct-2010 - It’s a familiar situation for all car drivers. In the autumn, when the roads are foggy, visibility drops below 50 metres. The light of the car’s headlights are scattered by the drops of fog, meaning we can’t see objects further away because the light can’t reach them. This everyday example ...
Spying on Plastic Production
On-line Monitoring of Particle Growth in Catalytic Polyethylene Slurries
08-Jan-2010 - Real-time monitoring of high-density polyethylene (HDPE) production is now possible. In an article in the journal Macromolecular Reaction Engineering, Professor Rolf Mülhaupt and his student Rainer Xalter of Albert-Ludwigs University in Freiburg, Germany, describe how they use a combination of ...
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