44 Current news of Angewandte Chemie
rss |
You can refine your search further. Select from the filter options on the left to narrow down your results. |
Fast, uncomplicated, and specific: diagnosis of prostate cancer from blood samples
24-Aug-2022
Early detection of prostate cancer, one of the most common types of cancer in men, is often achieved with PSA tests. However, this blood test for prostate-specific antigens gives many false positive results, causing unnecessary biopsies and overtreatment. In the journal Angewandte Chemie, a ...
Sensor with separation capability: diagnosing jaundice using tear fluids
28-Jun-2022
Human tear fluids contain many proteins, metabolites, and other molecules whose concentrations change significantly with certain diseases. A research team has now developed a handy test kit for tears that can identify patients with jaundice. Their success is based on a hybrid sensor that ...
Luciferin synthesis and organophosphate detection by a luminescent enzymatic cascade
16-Mar-2022
A luminescence reaction modeled on fireflies can detect contamination with organophosphates with high sensitivity, ease, and low cost. At the center of this technology is a new enzymatic method for the synthesis of analogues of luciferin, the substance that makes fireflies glow. As reported by a ...
Tracking the NO signaling pathway
26-Aug-2021
Both nitric oxide (NO) and hydrogen sulfide (H2S) act as gaseous signaling molecules with similar physiological effects. Many of the critical questions about the interplay between these two gasotransmitters hinge on their chemical reactivity and the fleeting existence of HSNO, a key product of ...
Interference leads to inaccurate Raman spectroscopic analysis of vitamin B12
25-Aug-2021
Many natural products are complicated organic molecules. Despite this complexity, scientists are usually able to investigate them using spectroscopic techniques. However, a team of researchers has now discovered that care should be taken using Raman spectroscopy to analyze certain chiral ...
Ultrafast charge transfer in Prussian blue analogues
23-Aug-2021
Photoinduced charge transfers are an interesting electronic property of Prussian blue and some analogously structured compounds. A team of researchers has now been able to elucidate the ultrafast processes in the light-induced charge transfer between iron and manganese in a manganese-containing ...
Stable and Functional Dyes for Near-Infrared Fluorescence Imaging of Living Subjects
05-Jun-2020
Scientists can monitor biomolecular processes in live tissue by noninvasive optical methods, such as fluorescence imaging. However, the fluorescent dyes used for that purpose are often rather unstable, and photobleaching, lack of specificity, and poor pharmacokinetics are recurrent issues. US ...
Ultrafast repeated staining and destaining of cell samples for tumor diagnostics
27-Mar-2020
In the treatment of tumors, microenvironment plays an important role. It often contains immune cells that are so changed that they promote tumor growth. In the journal Angewandte Chemie, scientists have introduced a method by which cell samples from tumors and their surroundings can rapidly ...
Cancer Diagnostics
18-Mar-2020
A good indicator of dysregulation in live cells is a change in their RNA expression. MicroRNA (miRNA), a special type of RNA, is considered a biomarker for carcinogenic cells. A team of scientists from China has found a way to amplify miRNA in live tumor cells for bioimaging. As they report in ...
Molecular probe maps misfolded proteome state in live cells
13-Jan-2020
The folding state of the proteins in live cells often reflect the cell’s general health. Australian scientists have developed a molecular probe that senses the state of the proteome—the entire set of the proteins—by measuring the polarity of the protein environment. The fluorescence signal of the ...
