QIAGEN announced the appointment of Thomas Ebeling, a leading international executive with extensive experience in the healthcare, media and consumer goods industries, as a member of the Supervisory Board with immediate effect. Mr. Ebeling joins QIAGEN as part of a process launched by the S ... more
QIAGEN adds promising genomic biomarkers to pipeline
Mutations of SF3B1 gene indicate favorable prognosis for patients with bone marrow disorders
QIAGEN N.V. announced it has acquired an exclusive global license to the biomarker SF3B1 from the University of Tokyo. SF3B1 is believed to play a critical role in the prognosis of patients with myelodysplastic syndromes (MDS), a group of hematological cancers in which bone marrow does not produce enough healthy blood cells. Mutations of this gene, which is an important component of the spliceosome machinery, indicate a more favorable disease progression for patients than the “wild-type” gene, so testing for these gene variants could potentially provide important guidance for treatment based on a personalized healthcare approach to MDS.
"This novel biomarker adds important content to QIAGEN’s market-leading position in molecular tests for blood cancers. Our assays and panels cover the full range of these malignancies, including the bone marrow failure disorders known as myelodisplastic disorders. The SF3B1 biomarker is included in our GeneReadTM DNAseq Leukemia V2 gene panel for next-generation sequencing," said Vincent Fert, QIAGEN’s Personalized Healthcare Program Leader. “Building on a broad portfolio of molecular diagnostics for blood cancers, QIAGEN continues to partner with clinical researchers at pharmaceutical companies and academic centers, to extend the benefits of personalized healthcare. Because several Pharma companies are developing potential anti-cancer drugs targeting the SF3B1 gene, this biomarker also holds potential for co-development as a companion diagnostic.”
QIAGEN licensed the SF3B1 biomarker in an ongoing expansion of the oncohematology offering for clinical research and diagnostics. Three additional spliceosome biomarkers implicated in various blood cancers and targeting variants in the U2AF35 (U2AF1), ZRSR2 and SFRS2 genes are also part of the license agreement.
- myelodysplastic syndromes
- University of Tokyo
QIAGEN N.V. announced the acquisition of the remaining 80.1% of diagnostics instruments company NeuMoDx Molecular, Inc. for $248 million in cash. The move rounds out QIAGEN’s portfolio of automated molecular testing solutions based on the proven PCR technology. The transaction was completed ... more
Thermo Fisher Scientific Inc. and QIAGEN N.V. announced that they have entered into an amendment to their acquisition agreement under which Thermo Fisher has commenced a tender offer to acquire all of the ordinary shares of QIAGEN. The amendment provides for an increase from the original of ... more
A keen sense of smell is a powerful ability shared by many organisms. However, it has proven difficult to replicate by artificial means. Researchers combined biological and engineered elements to create what is known as a biohybrid component. Their volatile organic compound sensor can effec ... more
Scientists from the Technical University of Munich (TUM) and the University of Tokyo have developed an ultrathin pressure sensor that can be attached directly to the skin. It can measure how fingers interact with objects to produce valuable data for technological or medical applications. Th ... more
For the first time, researchers have managed to view previously inaccessible details of certain chemical processes. They have shown there are significant discrete stages to these processes which build on our knowledge of chemical synthesis. These details could aid in the development of meth ... more
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