The chromatographic purification of natural substances is often a challenge due to the complex starting materials. The silicafree alternative more
Cost-efficient purification of natural compounds
Slica-free alternative to traditional HPLC columns for extraction, also from crude extractsLauren Pahnke, Field Applications Specialist, Gilson
Principle behind CPC (Centrifugal Partition Chromatography)
CPC column design
CPC purification of CBD and THC from cannabis oil using a Gilson CPC 250 PRO and PLC 2250 Purification System
Chromatographic purification of natural compounds presents many challenges to scientists because of the complex nature of the starting matrices that are used in the process.
These starting materials can damage traditional columns and cartridges, decreasing the length of their usage and increasing costs; that is, if the particular system can even accommodate the starting material.
Centrifugal partition chromatography (CPC), which uses both liquid stationary and mobile phases, can handle heavily contaminated, complex starting materials, such as direct extracts from many biological sources, and has been shown useful for the isolation of piperine from Pipernigrum, gingerol from ginger and hundreds of other natural compounds from plants.
Additionally, by relying on a liquid stationary phase, CPC columns do not need to be replaced like traditional columns and cartridges used by preparative HPLC and flash chromatography methods.
This article will discuss the basic principles behind CPC and explore the use and benefits of CPC in the purification of cannabinoids from crude cannabis oil.
TRACKMAN Connected is a tablet with exclusive accessories and applications that make pipetting on 96- and 384-well plates faster and more reliable more
CPC is a highly efficient liquid-liquid system that can be integrated into any system instead of a classical column. more
Bring traceability and reliability to the bench through our Bluetooth-enabled tablet and pipetting system, TRACKMAN® Connected. Designed to communicate with PIPETMAN® M Connected via Bluetooth®, the tablet interacts in real-time with the pipette and guides you through your protocol with Pip ... more
Gilson is pleased to announce the acquisition of Armen SAS. "The addition of the Armen Instruments product line allows Gilson to strengthen its purification solutions for every sample type, from manual to automated systems, addressing lab, pilot, and process scale solutions." said Atika El ... more
GILSON S.A.S. announced the appointment of new UK distributors in addition to establishing a new UK accredited service facility for UK customers. With effect from 1st January 2010, Scientific Laboratory Supplies (SLS) is now the official distributor for these brands. Commenting on this ne ... more
Gilson, Inc. announced the opening of the Gilson Service Center of Excellence. Located in Middleton, Wisconsin, the new state-of-the-art facility offers pipette repair, calibration and certification for pipette customers located throughout the United States. Every aspect of the new service ... more
- 1Microwave freeze drying of fruits & vegetables
- 2Getting Particular about Particles and Porosity
- 3Asymmetric Flow Field Flow Fractionation (AF4) - A Powerful Method for Polymer Characterization
- 4Field-Flow Fractionation - The Universal Separation Principle for Particle and Macromolecule Characterization
- 5A guideline: Why knowledge of particle size is so important
- 6Comparing ICP-OES Analyzers' Plasma Views: Axial, Radial, Dual, MultiView, and New Dual Side-On Interface
- 7Automated Dynamic Light Scattering
- 8Polyether-Modified Silicones for Cosmetic Applications
- 9ETC Powder Dispensing Study
- 10Burn injuries under freezing (labor protection) conditions?