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Alpacas provide blueprints for mini-antibodies
30-Jul-2021
A team of researchers has developed mini-antibodies that efficiently eliminate the SARS-CoV-2 coronavirus and its dangerous new variants. The so-called nanobodies bind and neutralize the virus up to 1000 times better than previously developed mini-antibodies. In addition, the researchers were ...
22-Mar-2021
Scientists working with Stefan Hell at the Max Planck Institute (MPI) for Biophysical Chemistry in Göttingen and the Heidelberg-based MPI for Medical Research have developed another light microscopy method, called MINSTED, which resolves fluorescently labeled details with molecular sharpness. ...
Researchers first to succeed in filming a phase transition with extremely high spatial and temporal resolution
26-Jan-2021
Laser beams can be used to change the properties of materials in an extremely precise way. This principle is already widely used in technologies such as rewritable DVDs. However, the underlying processes generally take place at such unimaginably fast speeds and at such a small scale that they ...
Novel technique visualizes individual atoms in a protein with cryo-electron microscopy for the first time
23-Oct-2020
A crucial resolution barrier in cryo-electron microscopy has been broken. Holger Stark and his team at the Max Planck Institute (MPI) for Biophysical Chemistry have observed single atoms in a protein structure for the first time and taken the sharpest images ever with this method. Such ...
New molecular details from mitochondria
14-Aug-2020
Super-resolution MINFLUX nanoscopy, developed by Nobel laureate Stefan Hell and his team, is able to discern fluorescent molecules that are only a few nanometers apart. In an initial application of this technique to cell biology, researchers led by Stefan Hell and Stefan Jakobs have now optically ...
16-Dec-2019
Vaccinia viruses serve as a vaccine against human smallpox and as the basis of new cancer therapies. Two studies now provide fascinating insights into their unusual propagation strategy at the atomic level. For viruses to multiply, they usually need the support of the cells they infect. In many ...
15-Aug-2016
An international team of scientists from Austria, Germany and the US has combined newly developed techniques in electron microscopy and protein assembly to elucidate how cells regulate one of the most important steps in cell division. When one cell divides into two - that is how all forms of life ...
Every atom counts
08-Aug-2016
Malignant cancer cells not only proliferate faster than most healthy cells in our bodies. They also generate more “junk”, such as faulty and damaged proteins. This makes cancer cells inherently more dependent on the most important cellular garbage disposal unit, the proteasome, which degrades ...
Max Planck scientists in Goettingen have for the first time made finest details of nerve cells in the brain of a living mouse visible
08-Feb-2012
To explore the most intricate structures of the brain in order to decipher how it functions – Stefan Hell's team of researchers at the Max Planck Institute for Biophysical Chemistry in Göttingen has made a significant step closer to this goal. Using the STED microscopy developed by Hell, the ...
With a groundbreaking idea the physicist has overcome the diffraction resolution barrier in optical microscopy
08-Jul-2011
Prof. Dr. Dr. h. c. Stefan Hell of the Max Planck Institute for Biophysical Chemistry in Göttingen is to receive the 2011 Körber European Science Prize endowed with 750,000 euros for his pioneering discoveries in the field of optics. Every year, the Körber Prize is awarded to an outstanding ...
