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New insights into the utilization of nanotechnology-based drugs

How nanoparticles get inside cells and release drugs


Novel drugs, such as vaccines against covid-19, among others, are based on drug transport using nanoparticles. Whether this drug transport is negatively influenced by an accumulation of blood proteins on the nanoparticle’s surface was not clarified for a long time. Scientists at the Max Planck ...


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Quantum simulator enables first microscopic observation of charge carriers pairing

Research results could be key to understanding high-temperature superconductors


A team of researchers at the MPQ has for the first time monitored in an experiment how holes (positive charge carriers) in a solid-state model combined to form pairs. This process could play an important role in understanding high-temperature superconductivity. Using a quantum simulator, ...


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The architecture of shattered genomes

Hunting for disease clues in the dark matter of our DNA


Scientists have reconstructed the chromosomes of patients with an extremely high number of aberrations in their genome that could alter the expression of nearby genes and potentially cause disease. Their results were published in Nature Communications in October 2022. “We are only beginning to ...


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Researchers cast new light on magnons to verify topological phases in magnetic materials

“Raman scattering is a standard experimental technique available in many labs, which is one of the strengths of this proposal”


Much recent research has focused on ‘topological’ materials – an intriguing type of solids which fall outside the standard classification into insulators and conductors. While their bulk is insulating, these phases are characterized by electrically conducting channels which appear at their edges. ...


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AI detects rare forms of dementia

Researchers use new techniques to detect patterns in imaging data and enable early diagnosis


Researchers at MPI CBS and University of Leipzig Medical Center have used new artificial intelligence (AI) and machine learning techniques to detect rare forms of dementia on MRI images. In their study, the researchers show that AI can automatically recognize patterns in patient imaging data that ...


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With light into the nanoworld: How optical microscopes allow detailed investigations of nanoparticles

The goal: the development of novel nanoparticles for biomedical applications.


It sounds like trying to scan a vinyl record with a hammer: Light is actually too "coarse" to image small particles on the nanometer scale. However, in their project "Supercol"- funded by the European Union - scientists want to achieve just that: The investigation of nanoparticles with light. To ...


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Neuroscientists illuminate how brain cells deep in the cortex operate in freely moving mice

This new miniature microscope is a game changer for exploring the link between neural activity and complex animal behavior


How can we see what neurons deep in the cortex are doing during behavior? Researchers at the Max Planck Institute for the Neurobiology of Behavior - caesar (MPINB) have developed a miniature microscope small enough to be carried on the head of a freely moving mouse and capable of measuring ...


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Measuring Organ Development

Metrics for organ development have now been defined for the first time


Researchers from Dresden and Vienna reveal link between connectivity of three-dimensional structures in tissues and the emergence of their architecture to help scientists engineer self-organising tissues that mimic human organs. Organs in the human body have complex networks of fluid-filled tubes ...


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Show me your brain scan and I'll tell you how old you really are

Artificial neural networks will play an increasingly important role in medical diagnosis


The biological age of a person can be accurately determined from brain images using the latest AI technology, so-called artificial neural networks. Until now, however, it was unclear which features these networks used to infer age. Researchers at the Max Planck Institute for Human Cognitive and ...


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More than microscopes can show

Computer simulations visualize how an essential stem cell protein opens wrapped DNA


A key protein for converting adult stem cells into cells that resemble embryonic stem cells has been visualized in unprecedented detail by an international team of researchers around Hans Schöler and Vlad Cojocaru of the Max Planck Institute for Molecular Biomedicine in Münster. By combing ...


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