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MaxDIA – taking proteomics to the next level

Highly sensitive and accurate data analysis: New software improves data-independent acquisition proteomics

12-Jul-2021

Proteomics produces enormous amounts of data, which can be very complex to analyze and interpret. The free software platform MaxQuant has proven to be invaluable for data analysis of shotgun proteomics over the past decade. Now, Jürgen Cox, group leader at the Max Planck Institute of ...

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How ethane-consuming archaea pick up their favorite dish

Scientists sucessfully decoded the structure of the enzyme responsible for ethane fixation

09-Jul-2021

Hot vents in the deep sea are home to microbes that feed on ethane. They were discovered recently from scientists of the Max Planck Institute for Marine Microbiology. Now the researchers from Bremen succeeded in finding an important component in the microbial conversion of the gas. They were able ...

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How a corona infection changes blood cells in the long run

Method could help as an early warning system to detect future pandemics by unknown viruses

22-Jun-2021

Using real-time deformability cytometry, researchers at the Max-Planck-Zentrum für Physik und Medizin in Erlangen were able to show for the first time: Covid-19 significantly changes the size and stiffness of red and white blood cells - sometimes over months. These results may help to explain why ...

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Piecing together the full picture of the genome

Revolutionary new DNA sequencing method enables unparalleled rapid, accurate, and efficient analysis while preserving the full picture of a genome

17-Jun-2021

A team of international researchers from the Friedrich Miescher Laboratory of the Max Planck Society developed a new DNA sequencing method that provides fast and efficient tracking of genetic information. Their new technique called haplotagging now enables scientists to quickly and precisely ...

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Nucleosome breathing from atomistic time snapshots

Computer simulations visualize in atomic detail how DNA opens while wrapped around proteins

08-Jun-2021

Researchers from the Hubrecht Institute in Utrecht (The Netherlands) and the Max Planck Institute for Molecular Biomedicine in Münster (Germany) used computer simulations to reveal in atomic detail how a short piece of DNA opens while it is tightly wrapped around the proteins that package our ...

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Enantiomorph distribution maps for metals and metallic alloys

07-Jun-2021

The spatially resolved determination of which of the two enantiomorphic structural variants - the left-handed or the right-handed - of a chiral phase is present in a polycrystalline material is the focus of a publication in Science Advances. With the EBSD (electron backscatter diffraction) -based ...

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Researchers reveal another secret of photosynthesis

Chemical isomerism in Nature’s water splitting catalyst may explain the high efficiency of the photosynthetic reaction

01-Jun-2021

Green hydrogen is often said to be “the petroleum of tomorrow”. For a climate-neutral energy supply in the future, we must turn away from carbon-based sources and harness solar fuels. The road ahead is long and requires, among other things, a precise knowledge of the functional principles of ...

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Highly Accurate Results at Low Computational Cost

Researchers Succeed in Predicting NMR Parameters with DLPNO Approximation

20-May-2021

Nuclear magnetic resonance (NMR) is one of the most important analytical techniques used in chemical, pharmaceutical, and biomedical research as well as in materials sciences. It provides detailed information about the structures of molecules in solution, which is, however, indirect. Hence, ...

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More than the sum of mutations

165 new cancer genes identified with the help of machine learning

19-Apr-2021

A new algorithm can predict which genes cause cancer, even if their DNA sequence is not changed. A team of researchers in Berlin combined a wide variety of data, analyzed it with “Artificial Intelligence” and identified numerous cancer genes. This opens up new perspectives for targeted cancer ...

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Speeding up sequence alignment across the tree of life

A sequence search engine for a new era of conservation genomics

09-Apr-2021

A team of researchers from the Max Planck Institutes of Developmental Biology in Tübingen and the Max Planck Computing and Data Facility in Garching develops new search capabilities that will allow to compare the biochemical makeup of different species from across the tree of life. Its ...

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