Glycation in the body: Trigger of protein dysfunction in aging and age-related diseases
Study powerfully demonstrates how the consequences of glycation for the whole proteome can be studied
01-Apr-2022 -
To maintain organ functions, the proteins in the cells need to be kept in balance (proteostasis). This state is disturbed with increasing age. One possible cause is glycation, in which sugars and proteins combine irreversibly. These advanced glycation end products (AGEs) accumulate and can lead ...
age-related diseases
cellular aging
Maillard Reaction
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