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4 Current news of Howard Hughes Medical Institute

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Expanding the optogenetics toolkit

22-Oct-2018 - Controlling individual brain cells using light-sensitive proteins has proven to be a powerful tool for probing the brain's complexities. As this branch of neuroscience has expanded, so has the demand for a diverse palette of protein tools. A multidisciplinary team of 14 researchers from the ...

brain evolution genes +7
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DNA study casts light on century-old mystery of how cells divide

22-Jan-2018 - Scientists have solved a longstanding puzzle of how cells are able to tightly package DNA to enable healthy cell division. Their findings shed light on how single cells can compact DNA 10,000-fold to partition it between two identical cells - a process that is essential for growth, repair and ...

analysis biology cell biology +5
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Imaging techniques set new standard for super-resolution in live cells

31-Aug-2015 - Scientists can now watch dynamic biological processes with unprecedented clarity in living cells using new imaging techniques developed by researchers at the Howard Hughes Medical Institute's Janelia Research Campus. The new methods dramatically improve on the spatial resolution provided by ...

cells photoactivated localization microscopy STED microscopy

Researchers 'unzip' molecules to measure interactions keeping DNA packed in cells

29-Jan-2009 - Anyone who has ever battled a stuck zipper knows it's a good idea to see what's stuck, where and how badly - and then to pull hard. A Cornell research team's experiments involve the "unzipping" of single DNA molecules. By mapping the hiccups, stoppages and forces along the way, they have gained ...

bases enzymes genes +5