Learn how to save valuable resources by combining critical characterization assays into one real-time platform. more
Discover the future of HPLC and ELISA today
Perform antibody characterizations in real-time and high-throughput
Automated Octet® platform for enhanced productivity.
Typical clone selection and optimization workflow with typical screens/tests performed at each stage. Expression and titer are screened earlier in the workflow, while product quality (PQ) attributes are assessed later due to screening limitations.
Workflow of titer analysis and glycan screening on Octet® platform.
Whilst traditional methods of antibody quantitation require highly trained personnel to use specialized instrumentation (HPLC) or are considerably time consuming (ELISA), the Octet® system delivers a platform for cell line development scientists to rapidly quantify antibody titer, quickly select optimal clones and reduce development time for biologics.
Combining quantitation assays with a novel GlyS Kit allows to perform both titer and sialic acid content screening on the same sample. There is no need for sample purification or glycan digestion steps.
Learn how to save valuable resources by combining critical characterization assays into one real-time platform.
Bio-Layer Interferometry (BLI) allows for the evaluation of multiple product properties such as titer, antigen binding or glycan content, offering users a key benefit over comparative technologies. A new Sialic Acid (GlyS) kit facilitates screening for sialic acid on the Octet® systems using ready-to-use biosensors and kit reagents, thereby enabling the screening of up to 1000 antibody clones in just one hour. Download the application overview to learn how the sialic acid screening assay can be combined with an IgG titer assay using Protein A/G coated biosensors to provide both titer and sialic acid content determination from the same sample in one assay.
- antibody characterization
- antibody quantitation
- cell line development
- bio-layer interferometry
- glycan screening
- titer screening
Colonies are imaged and selected based on user-defined parameters. Plate handling, barcode reading and picking are fully integrated accelerating cell line development more
Discover a high-throughput automated solution for imaging and analyzing mammalian cells. Detailed imaging and comprehensive data analysis enable better decision making more
The QPixTM Series can pick up to 3000 clones per hour with a typical efficiency of >98%, significantly increasing speed, throughput and walk-away time. more
Rapid determination of the growth of cell lines is important for a number of processes, such as optimization of cell culture conditions and verification of monoclonality. However, conventional techniques are time-consuming, subjective and may risk interference with cell growth. Save time an ... more
The technology in ClonePix Systems removes the need for serial dilution or cell-sorting techniques. It allows monoclonal populations of high-secreting cells to be established in a much shorter time frame, removing many of the bottlenecks associated with producer cell-line optimization and d ... more
Conventional picking and screening methods are often laborious when multiple selections are required. The QPix 400 Series of Microbial Colony Pickers allow you to simultaneously detect colonies and quantify fluorescent markers when pre-screening colonies before picking. This automated micro ... more
Molecular Devices, LLC announced that its European Patent No. 1802752 titled “Parallel Patch Clamp System” was upheld by the European Patent Office in its original form, following a recent Opposition Proceeding. Molecular Devices’ patent went through Opposition Proceedings before the Opp ... more
- 1Microwave freeze drying of fruits & vegetables
- 2Asymmetric Flow Field Flow Fractionation (AF4) - A Powerful Method for Polymer Characterization
- 3Comparing ICP-OES Analyzers' Plasma Views: Axial, Radial, Dual, MultiView, and New Dual Side-On Interface
- 4Field-Flow Fractionation - The Universal Separation Principle for Particle and Macromolecule Characterization
- 5Getting Particular about Particles and Porosity
- 6Automated Dynamic Light Scattering
- 7Benefits of Deep Learning and AI in Microscopy: Label-Free Nucleus Detection in Micro Well Plates
- 8Risks and Hazards Caused by ELECTROSTATICS in the LAB?!
- 9Polyether-Modified Silicones for Cosmetic Applications
- 10ETC Powder Dispensing Study