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Rare genetic disorders: new approach uses RNA in search for genetic triggers
14-Jun-2017 - In about half of all patients with rare hereditary disorders, it is still unclear what exact position of the genome is responsible for their condition. One reason for this is the enormous quantity of information encoded in human genes. Scientists from the fields of informatics and medicine have ...
Stem cell factor Nanog knows when to slow down
28-Nov-2016 - The transcription factor Nanog plays a crucial role in the self-renewal of embryonic stem cells. Previously unclear was how its protein abundance is regulated in the cells. Researchers at the Helmholtz Zentrum München and the Technical University of Munich, working in collaboration with ...
10-Nov-2016 - Certain proteins in the blood of children can predict incipient type 1 diabetes, even before the first symptoms appear. A team of scientists at the Helmholtz Zentrum München, partners in the German Center for Diabetes Research (DZD), reported these findings. The work was based on two large ...
20-Jul-2016 - Working with colleagues from the ETH Zürich, scientists at the Helmholtz Zentrum München and the Technical University of Munich have developed software that allows observing cells for weeks while also measuring molecular properties. Certain questions in modern cell biology can only be answered by ...
19-Jul-2016 - Scientists at the Helmholtz Zentrum München have developed a new mass spectrometry imaging method which, for the first time, makes it possible to analyze hundreds of metabolites in fixed tissue samples. Their findings, published in the journal Nature Protocols, explain the new access to metabolic ...
Precisely where the polymerase is changed
25-Jan-2016 - Scientists at the Helmholtz Zentrum München, working with colleagues from the Ludwig-Maximilians-Universität München, have developed a method for the thorough analysis of protein modifications. They mapped the phosphorylation sites of the RNA polymerase II enzyme, which is responsible for ...
26-Oct-2015 - Monocytes are white blood cells that are crucial to human immune defense. They are precursor cells of macrophages and dendritic cells and are circulating in the blood until they invade their respective target tissue where they defend the body against exogenous structures. So far, scientist ...
02-Jul-2015 - Radiation therapy is an important part of breast cancer treatment. Sometimes, however, tumor cells become increasingly resistant to radiation damage. Now, scientists of Helmholtz Zentrum München have developed a 3D microtissue-based screening system which, for the first time, enables them to test ...
11-Sep-2014 - he recently developed fluorescent protein Amrose is now being used for advanced near-IR imaging procedures. With the aid of a novel evolutionary platform technology, scientists at the Helmholtz Zentrum München have developed this infrared marker as part of a combined effort to improve the quality ...
14-Jan-2008 - Researchers at the Helmholtz Zentrum München - German Research Center for Environmental Health, together with the University of Oregon, USA have developed a new image reconstruction system for computed tomography that produces greater image quality at a lower radiation dose compared with standard ...
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