Scientists develop “scifi-RNA-seq” method for ultra-high-throughput RNA sequencing in single cells

An efficient high-throughput method with a wide range of applications

02-Jun-2021 - Molecular analysis of single cells provides an important basis for precision medicine. Five years ago, scientists around the world came together to pursue the “Human Cell Atlas” project, with the aim of cataloging all cells in the human body. These data have helped, for example, to identify those ...

The body as a network

A new VR platform enables the display of huge amounts of data. This can be helpful in the study of rare genetic defects, among other things

27-Apr-2021 - Networks offer a powerful way to visualize and analyze complex systems. However, depending on the size and complexity of the network, many visualizations are limited. Protein interactions in the human body constitute such a complex system that can hardly be visualized. Jörg Menche, Adjunct ...

Study of hundreds of proteins in parallel

First highly scalable method developed to monitor protein levels and localizations in cells

20-Nov-2020 - CeMM researchers have developed a highly scalable method which allows for the study of hundreds of proteins in parallel in order to monitor the changes of their levels and localization in the cell. This novel strategy is a notable contribution, not only to drug development for future treatments ...

Single-cell RNA seq method developed to accurately quantify cell-specific drug effects in pancreatic islets

Findings could open up potential therapeutic avenues to treat Type 1 diabetes

14-May-2020 - Researchers from Stefan Kubicek’s and Christoph Bock’s groups, at the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences in Vienna, have developed a method to accurately assess the effect of specific drugs in isolated pancreatic tissue by using a refined single-cell ...

First SARS-CoV-2 genomes in Austria openly available

07-Apr-2020 - The first 21 SARS-CoV-2 genomes in Austria have now been completed and published within the scope of the “Mutational Dynamics of SARS-CoV-2” project recently launched by CeMM in close collaboration with the Medical University of Vienna. The project aims at sequencing 1,000 viral genomes obtained ...

Novel mathematical framework provides a deeper understanding of how drugs interact

15-Nov-2019 - Researchers at the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences have developed a new methodology characterizing more precisely how drugs influence each other when combined during treatment. Their analysis of over 30k drug pairs applied to cell lines identified ...

Pharmacoscopy: Next-Generation Microscopy

New possibilities for drug discovery

26-Apr-2017 - A novel microscopy method allows unprecedented insights into the spatial organization and direct interactions of immune cells within blood and other liquid multi-lineage tissues. The assay, called “Pharmacoscopy”, developed and patented by scientists from CeMM Research Center for Molecular ...

Exhaled diagnosis – what your breath can reveal about your health

07-Mar-2013 - Analytical chemists have measured the levels of selected organic compounds found in human breath, with the aim of one day applying the technique to the routine diagnosis of disease. The analysis of biomarkers in exhaled air and in blood can reveal the presence of cancer, the rejection of organs ...