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7 Current news of berliner-institut-fuer-gesundheitsforschung-bih

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How stem cells and immune cells communicate

Lisec Artz Award for Simon Haas: Groundbreaking discovery of an unknown protective mechanism against blood cancer from stem cells

17-Nov-2023 - Blood cancer is often driven by mutations in stem cells, which are key target cells in the search for innovative early-stage therapies. Dr. Simon Haas, head of a lab within the joint research focus of the Berlin Institute of Health at Charité (BIH), Charité – Universitätsmedizin Berlin, and the ...

blood cancer blood cells cancer +4
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Rare kidney disease is genetically decoded

The entire genome of a human being can be analysed on a single sequencing chip

25-Aug-2023 - Bartter syndrome type 3 is the result of several structural variants in the genome. By using long-read sequencing, Janine Altmüller and her team from the Max Delbrück Center, the BIH and University Hospital Cologne mapped out the rare disease in unprecedented detail. They have now reported their ...

gene variants genetic analysis kidney diseases +1
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DNA analysis reveals risk of post-meal insulin resistance

Targeted intervention may be possible

14-Jun-2023 - Scientists from the Berlin Institute of Health at Charité (BIH), along with colleagues from the United Kingdom, have found clues as to how we maintain constant blood sugar levels after we have eaten. Analyzing the DNA of nearly 55,000 participants from different studies, they identified ten ...

blood sugar diabetes DNA analytics +5
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The predictive power of blood: metabolomic profiling reveals risk of multiple diseases all at once

Striving for early risk identification and preventive action

26-Sep-2022 - To prevent diseases from occurring in the first place, it is important to identify those individuals who are at particularly high risk as early as possible. Yet current screening methods are often costly and focus only on one disease at a time. Scientists from the Berlin Institute of Health at ...

artificial intelligence blood analysis metabolomic studies
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The subtle difference: Pancreatic tumor organoids pave the way for single-cell diagnostics

A valuable experimental model for future therapies

16-Nov-2021 - The prognosis for pancreatic cancer is usually grim: The tumors are often detected too late and are then difficult to treat. Yet a small percentage of patients survive many years after diagnosis. Scientists from the Berlin Institute of Health at Charité (BIH) have now grown organoids from various ...

cancer cancer diagnostics pancreatic cancer +2
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New software detects disease-causing gene mutations

Software finds "needle in a haystack" e.g. in the diagnosis of rare diseases

10-Sep-2020 - A serious illness is often the result of a single genetic defect. But given that two healthy people already have around three million differences in their genetic make-up, it is no easy task to pick out the one disease-causing deviation from the many harmless gene variants. Scientists at the ...

genetic analysis hereditary diseases rare diseases +1
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Precise diagnostics with artificial intelligence

BIH Digital Health Accelerator guides Aignostics GmbH through its spin-off

27-Apr-2020 - The usual way to determine if a suspicious lump is cancerous involves microscopic examination in a pathology laboratory. To ease the workload of pathologists who face a rising number of cancer cases and increasingly finer molecular details and to enable tailored treatments, scientists at the ...

artificial intelligence cancer diagnostics diagnostics +2