Diseases - 6 News by Berliner Institut für Gesundheitsforschung (BIh)

Diseases - 6 News by Berliner Institut für Gesundheitsforschung (BIh)

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Largest study to date on the genetics of blood proteins highlights new disease mechanisms and drug repurposing opportunities

Machine learning combined with genetic analysis is expected to enable a more targeted use of active substances in precision medicine

08-May-2026 - Involving a collaboration with 118 investigators contributing from 89 institutions, scientists from the and Berlin Institute of Health at Charité (BIH) and the Precision Healthcare University Research Institute (Queen Mary University of London) have led the world’s largest study on the genetic ...

diseases gene regulation genetics
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How genes affect our metabolism

Better prevention of heart disease thanks to genetics

09-Oct-2025 - A person's metabolism is as unique as their fingerprint, and so is their risk of developing certain diseases. A better understanding of the genetic influences on metabolism could open up new therapeutic options. Researchers at the Berlin Institute of Health at Charité (BIH) and Queen Mary ...

diseases amino acids blood
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Researchers decipher mechanisms of liver regeneration

Study shows that human organs can regenerate even after prolonged diseases and repetitive injury

28-May-2024 - Scientists from the Berlin Institute of Health at Charité (BIH) and Open Targets together with colleagues from the University of Cambridge, and Addenbrooke’s Hospital in Cambridge, UK, uncovered mechanisms driving regeneration of the liver during chronic liver disease. This regenerative process ...

diseases biopsies liver
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Rare kidney disease is genetically decoded

The entire genome of a human being can be analysed on a single sequencing chip

25-Aug-2023 - Bartter syndrome type 3 is the result of several structural variants in the genome. By using long-read sequencing, Janine Altmüller and her team from the Max Delbrück Center, the BIH and University Hospital Cologne mapped out the rare disease in unprecedented detail. They have now reported their ...

diseases gene analysis gene variants
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DNA analysis reveals risk of post-meal insulin resistance

Targeted intervention may be possible

14-Jun-2023 - Scientists from the Berlin Institute of Health at Charité (BIH), along with colleagues from the United Kingdom, have found clues as to how we maintain constant blood sugar levels after we have eaten. Analyzing the DNA of nearly 55,000 participants from different studies, they identified ten ...

diseases blood sugar diabetes
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New software detects disease-causing gene mutations

Software finds "needle in a haystack" e.g. in the diagnosis of rare diseases

10-Sep-2020 - A serious illness is often the result of a single genetic defect. But given that two healthy people already have around three million differences in their genetic make-up, it is no easy task to pick out the one disease-causing deviation from the many harmless gene variants. Scientists at the ...

diseases genetic analysis hereditary diseases
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