Zooming into a nuclear pore complex using a high-speed atomic force microscope reveals the selectivity barrier that filters the traffic of molecules passing between the cytoplasm and nucleus in eukaryotic cells. This is comprised of intrinsically disordered proteins known as FG Nucleoporins that resemble highly dynamic molecular “tentacles”.
0.02 - 0.12: Captured at 550 ms per frame; Playback = realtime
0.13 - 0.22: Captured at 1360 ms per frame; Playback = ~4x
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Perturbation-free studies of single molecules
Researchers of the University of Basel have developed a new method with which individual isolated molecules can be studied precisely – without destroying the molecule or even influencing its quantum state. This highly sensitive technique for probing molecules is widely applicable and paves ... more
Virtual screening for active substances against the coronavirus
The University of Basel is part of the global search for a drug to fight the rampant coronavirus. Researchers in the Computational Pharmacy group have so far virtually tested almost 700 million substances, targeting a specific site on the virus – with the aim of inhibiting its multiplicatio ... more
2D materials: arrangement of atoms measured in silicene
Silicene consists of a single layer of silicon atoms. In contrast to the ultra-flat material graphene, which is made of carbon, silicene shows surface irregularities that influence its electronic properties. Now, physicists from the University of Basel have been able to precisely determine ... more
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