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Precisely where the polymerase is changed
25-Jan-2016 - Scientists at the Helmholtz Zentrum München, working with colleagues from the Ludwig-Maximilians-Universität München, have developed a method for the thorough analysis of protein modifications. They mapped the phosphorylation sites of the RNA polymerase II enzyme, which is responsible for ...
08-Oct-2015 - Using subatomic resolution, researchers have gained insights into the dynamic modus operandi of two switch proteins which are responsible for the import of compounds into the nucleus and for cell growth. The team headed by Prof Dr Klaus Gerwert from the Department of Biophysics at the ...
11-Aug-2015 - The dull black plastic of the device on Joshua Pearce's desk belies its usefulness. Pearce picks up the box, which has a switch on the side and a small opening on top. A handful of vials sit in a bag nearby, and each would fit snugly in the opening. The set-up seems generic, even bland, except ...
07-Jul-2015 - A research group at Umeå University in Sweden has managed to capture and describe a protein structure that, until now, has been impossible to study. The discovery lays the base for developing designed enzymes as catalysts to new chemical reactions for instance in biotechnological applications. ...
Water movement as detection aid for molecules
26-Sep-2014 - Water is a ubiquitous solvent in all life sciences – sometimes referred to as the "matrix of life". Contrary to earlier assumptions, it is not a passive witness of biochemical processes; rather, it participates in them actively. By influencing the movement of water molecules surrounding their ...
26-Mar-2014 - Proteins are vital participants in virtually all life processes, including growth, repair and signaling in cells; catalysis of chemical reactions and defense against infection. For these reasons, proteins can provide critical signposts of health and disease, provided they can be identified and ...
Proposed transaction strengthens position in strategic growth market for enzymes
23-Sep-2013 - BASF announced that its U.S. affiliate, BASF Corporation, has entered into an agreement to commence a cash tender offer for all of the outstanding shares of common stock of the biotechnology company Verenium Corporation (VRNM) for US$4.00 per share. Based on all outstanding shares and including ...
14-Aug-2013 - The X-Zyme process launched by LANXESS is a technology for the beamhouse stage of the leather production process. “The use of two microbial enzymes in the soaking and liming noticeably improves the quality of the pelt, reduces the amount of waste and makes the entire process much more efficient,” ...
Rice University scientists find split, mutant protein serves as building block for synthetic biological circuits
18-Mar-2013 - Rice University researchers have found a way to divide and modify enzymes to create what amounts to a genetic logic gate. Biochemist Matthew Bennett and graduate student David Shis created a library of AND gates by mutating a protein from a bacterial virus. The well-understood protein known as T7 ...
Energy saving chaperone Hsp90
18-Jan-2012 - A special group of proteins, the so-called chaperones, helps other proteins to obtain their correct conformation. Until now scientists supposed that hydrolyzing ATP provides the energy for the large conformational changes of chaperone Hsp90. Now a research team from the Nanosystems Initiative ...
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