Induced pluripotent stem cells - 7 News
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Brain research with organoids
Scientists develop effective method to genetically modify brain organoids
23-May-2023 - Primates are among the most intelligent creatures with distinct cognitive abilities. Their brains are relatively large in relation to their body stature and have a complex structure. However, how the brain has developed over the course of evolution and which genes are responsible for the high ...
Milestone: Researchers have generated primordial germ cells from stem cells – a world’s first
A big step toward producing rhino gametes
13-Dec-2022 - To save the northern white rhinoceros from extinction, the BioRescue team is racing to create lab-grown egg and sperm cells of the critically endangered subspecies. The team has now reported a milestone in “Science Advances”: they have generated primordial germ cells from stem cells – a world’s ...
Induced pluripotent stem cells reveal causes of disease
Using single-cell analyses, researchers systematically searched for correlations between individual genetic variants in induced pluripotent stem cells
08-Mar-2021 - Induced pluripotent stem cells (iPSC) are suitable for discovering the genes that underly complex and also rare genetic diseases. Scientists from the German Cancer Research Center (DKFZ) and the European Molecular Biology Laboratory (EMBL), together with international partners, have studied ...
Customized programming of human stem cells
The results open new possibilities in research
02-Dec-2020 - Induced pluripotent stem cells (iPS) have the potential to convert into a wide variety of cell types and tissues. However, the "recipes" for this conversion are often complicated and difficult to implement. Researchers at the Center for Regenerative Therapies Dresden (CRTD) at TU Dresden, Harvard ...
Midbrain organoids for automated chemical screening and disease research
Max Planck Innovation licenses process for the generation of organ-like tissue aggregates to biotech company StemoniX
05-Nov-2020 - Sometimes hundreds of thousands of potential therapeutics need to be tested in large-scale, fully automated experiments to identify a single effective drug. Most compounds do not work as desired, and some are even toxic. Since the development of the induced Pluripotent Stem (iPS) Cell technology ...
Deciphering diabetes with "game-changing" human blood vessels from stem cells
18-Jan-2019 - Changes in blood vessels are the major cause of death and morbidity in diabetes. For the first time, scientists managed to grow perfect human blood vessels as organoids in a petri dish. This breakthrough engineering technology dramatically advances research of vascular dysfunction in diseases ...
New stem cell research could make lab mice redundant
06-Aug-2009 - Researchers from the University of Bath are embarking on a project to use stem cell technology that could reduce the number of animal experiments used to study conditions such as motor neurone disease. Dr Vasanta Subramanian, from the University’s Department of Biology & Biochemistry, will be ...
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