Agilent Technologies Inc. (NYSE:A) and Multiplicom N.V. today announced that they have signed a definitive agreement under which Agilent will acquire Multiplicom, a European diagnostics company with state-of-the-art genetic testing technology and products. Multiplicom, headquartered in Niel ... more
Agilent Technologies Secures Patent for CGH Assays
Agilent Technologies Inc. announced that it was awarded a significant patent for comparative genomic hybridization methods. CGH methods help researchers study genetics and cancer in both basic and clinical research.
The U.S. patent (No. 8,232,055) has claims for measuring copy number changes in genomic DNA, covering both one-color and two-color assays using oligonucleotide probes and samples with high-sequence complexity, such as human genomic DNA samples.
Agilent’s copy number method, commercially introduced in 2005, uses long oligonucleotide probes, enabling high specificity and sensitivity. For example, samples containing as low as 8 percent abnormal cells may be confidently analyzed with Agilent’s copy number method.
The method was originally developed to improve upon older copy number assays that use long genomic fragments such as bacterial artificial chromosomes. (BACs often contain repetitive regions.) The method also improves upon other oligonucleotide array assays, which depend on sample preparation methods that remove significant portions of the genomic DNA content. Agilent’s higher-resolution platform allows users to detect much smaller genomic aberrations throughout complex genomes.
- Agilent Technologies
- comparative genomic…
- oligonucleotide probes
Agilent Technologies Inc. announced that Dr. Rohit Bhargava has received an Agilent Thought Leader Award in recognition of his pioneering work in the development of infrared spectroscopic imaging, and its application to life sciences research. Dr. Bhargava is a founder professor of bioengin ... more
Agilent Technologies Inc. and Transcriptic Inc. have agreed to partner their technologies to provide a solution for convenient, broad scale synthetic and discovery biology research. Agilent continues its strong program of fostering innovation using the Agilent portfolio by collaborating wit ... more