Staining Cycles with Black Holes

Ultrafast repeated staining and destaining of cell samples for tumor diagnostics

27-Mar-2020 - In the treatment of tumors, microenvironment plays an important role. It often contains immune cells that are so changed that they promote tumor growth. In the journal Angewandte Chemie, scientists have introduced a method by which cell samples from tumors and their surroundings can rapidly ...

Manganese-based MRI contrast agent may be safer alternative to gadolinium-based agents

17-Nov-2017 - A team of Massachusetts General Hospital (MGH) researchers has developed a potential alternative to gadolinium-based contrast agents (GBCAs) for magnetic resonance imaging (MRI). In their report the team describes experiments showing in a primate model that the manganese-based agent Mn-PyC3A ...

Advanced EEG analysis reveals the complex beauty of the sleeping brain

09-Feb-2017 - Massachusetts General Hospital (MGH) investigators have developed a novel approach to analyze brainwaves during sleep, which promises to give a more detailed and accurate depiction of neurophysiological changes than provided by a traditional sleep study. In a report published in the January issue ...

Device may provide rapid diagnosis of bacterial infections

10-May-2016 - A team of Massachusetts General Hospital (MGH) investigators has developed a device with the potential of shortening the time required to rapidly diagnose pathogens responsible for health-care-associated infections from a couple of days to a matter of hours. The system also would allow ...

Scientists adopt new strategy to find Huntington's disease therapies

Large, international NIH-supported study uses precision medicine to tackle neurological disorders

11-Aug-2015 - Scientists searched the chromosomes of more than 4,000 Huntington's disease patients and found that DNA repair genes may determine when the neurological symptoms begin. The results may provide a guide for discovering new treatments for Huntington's disease and a roadmap for studying other ...

Microfluidic device allows collection, analysis of hard-to-handle immune cells

Ability to gently collect neutrophils may improve understanding of immune response to serious injury

01-Sep-2010 - A team led by Massachusetts General Hospital (MGH) scientists has developed a new microfluidic tool for quickly and accurately isolating neutrophils – the most abundant type of white blood cell – from small blood samples, an accomplishment that could provide information essential to better ...

Novel technology opens the door to the understanding of and possible treatments for obesity, diabetes, ageing and cancer

Seahorse Bioscience Announces the XF96 Extracellular Flux Analyzer for Cellular Bioenergetics

08-Oct-2008 - Seahorse Bioscience announced the release of the first ever analytical instrument for the kinetic measurement of mitochondrial oxygen consumption and cytoplasmic glycolysis in cells in a 96 well microplate. For the past 75 years tools for measuring cellular bioenergetics have been relatively ...