6 Current white paper about the topic liquid chromatography

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Field-Flow Fractionation - The Universal Separation Principle for Particle and Macromolecule Characterization

09-22-2010

High molecular weight polymers, bio molecules or particles in a range of a few nanometers up to several microns are more and more important in science and technology. Many applications are based on the specific properties of these materials. For this reason, an exact knowledge of the molar ...

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Automated Dynamic Light Scattering

11-09-2009

INTRODUCTION From the late 1980s commercial Dynamic Light Scattering (DLS) detectors started being used in commercial biophysical laboratories throughout the world. These instruments enabled size measurements of small volumes of proteins and other biomaterials in solution to be made, with ...

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Innovative column technology for liquid chromatography

06-29-2007

Application 1 Fast method development and upscaling shown by the example of a root extrakt. Rotor volume 200 ml, flow rate: 10 ml/min, detection UV 254 nm, solvent system: hexane-ethylacetate-methanol-water Fig. 1Fig. 2 Fig. 3 Fig. 4 The analytical HPLC chromatogram (Fig.1) shows the ...

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Do you see the complete picture?

"Triple Detection" in Gel Permeation Chromatography

11-11-2005

Gel permeation chromatography (GPC) or also named size exclusion chromatography (SEC) is the most often used method for determining the molecular weight of natural and synthetic macromolecules. One specific strength of this method lies in the fact that by the separation process the whole ...

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Accurate Mass and TIPTM: Two Dimensions for Elemental Composition Determination: microTOFTM Featuring Unique TIPTM

03-10-2005

The ESI-TOF mass spectrometers micrOTOF and micrOTOF focus do not only provide accurate mass measurements but additionally describe the True Isotopic Pattern TIPTM. For molecular formula generation this unique combination significantly reduces the number of possible formula candidates and the ...

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Half a Century of Chromatography with Agilent and Predecessors

One Century of Chromatography with Twsett (1903)

10-01-2004

Tswett originated the chromatography with his work about the separation of chlorophyll in 1903. For some time it was relatively quite around this new technology. Exceptions were the workings of Kuhn and Lederer (1931) as well as of Hesse (1936 and 1942). A break through succeeded to E. Cremer ...

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