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Complete traceability and excellent reliability of your measurement results

Regular calibrations of spectrophotometers are vitally important for securing measurement results. With UV/Vis calibration standards from an accredited DKD more

QuickTOCpurity - On-line-TOC in ultra pure water

The QuickTOCpurity easily satisfies the most stringent TOC monitoring requirements wherever pure water is produced or consumed more

News validation

• Almac Opens Analytical Labs in New US Headquarters

  Almac’s new 240,000 sq. ft. North American Headquarters, built on 40 acres in Souderton, PA, north of Philadelphia is part of the Almac Group’s integrated services solutions strategy. The new facility delivers full-service, integrated clinical packaging, drug supply management and technology solutio more

• Singapore Launches Infrastructure for Metrology in Chemistry (MiC)

  The National Metrology Centre (NMC) of the Agency for Science, Technology and Research (A*STAR) and the Health Sciences Authority (HSA) have jointly set up a national Metrology in Chemistry (MiC) infrastructure. Senior Minister of State for Trade and Industry and Education, Mr S. Iswaran announced t more

• Thermo Fisher Scientific and Intrinsic Bioprobes Announce Alliance in Mass Spectrometric Immunoassay (MSIA) Workflow Development

  Thermo Fisher Scientific Inc. and Intrinsic Bioprobes (IBI) Inc. announced an alliance to co-develop and market a mass spectrometry solution that will enable researchers to perform quantitative, high-throughput, high-resolution protein biomarker assays. The solution couples the specificity of immuno more

White papers validation

• Experimental Workflow for Fast and Accurate Genotyping of Scrapie-resistant/sensitive Sheep
  

  Several scientific studies support the claim that natural scrapie is associated with polymorphisms at three codons within the sheep prion protein (PrP) gene. Genotyping of these codons (codon 136 [alanine, valine], 154 [arginine, histidine], and 171 [glutamine, arginine, histidine]) might enable breeding of sheep flocks with high resistance to scrapie. Fast and reliable high-throughput genotyping of sheep is a major issue, since scrapie is a serious problem in several European countries. To address this, an experimental procedure for DNA preparation and PCR-based detection of codon 136, 154, and 171 polymorphisms was established. more

• Analysis of the DNA Methylation Patterns at the BRCA1 CpG Island
  

  Germ-line alterations of the BRCA1 gene confer a lifetime risk of 40% for ovarian cancers and of 40%-80% for ­breast cancers. It is likely that BRCA1 acts as a tumor suppressor gene. BRCA1 involvement in breast cancers does not seem to be restricted to familial cancers. Despite the absence of somatic mutations in the breast tissues, a down regulation of BRCA1 expression is associated with malignancy in human sporadic breast cancers. more

• Chemometric Spectroscopy
  

  Chemometric Spectroscopy is the term used to describe the direct combination of a spectroscopic measurement with a chemometric data evaluation procedure, typically a multivariate statistic method, so providing quick and reliable deduction of the qualitative and quantitative properties of a sample from its spectrum. A multi-linear regression (MLR) or partial least squares (PLS) regression is usually used for the quantitative determination of individual or combined parameters, while substance identification generally relies on techniques such as discriminant or cluster analysis. more

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