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New Parsum probe - fit for purpose PAT for granulation particle size monitoring

Particle size distribution is one of the key parameters in pharmaceutical powder processing.Granulation – a common method for improving powder flow properties and reducing segregation is often not easy to develop, scale-up and control. Fluid Bed top spray granulation – monitor granule growth ...

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The microcalorimetry of nanoparticles

In this webinar, find out how Isothermal Titration Calorimetry (ITC) can be used to characterize nanoparticles. Isothermal titration calorimetry (ITC) is used to characterize the thermodynamics of nanoparticle assembly, as well as nanoparticle interactions with proteins, membranes and other ...

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Co-crystal structure optimization using Isothermal Titration Calorimetry

The success rate for protein- or RNA/DNA-ligand co-crystallization can be significantly improved by performing preliminary biophysical analyses. Among suitable biophysical approaches, isothermal titration calorimetry (ITC) is certainly a method of choice.ITC can be used in a wide range of ...

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Characterize subvisible protein particles in formulations

Guest presenter - Prof. Dr. John Carpenter, University of ColoradoCounting and sizing of subvisible particles in therapeutic protein formulations are critically important activities for product development and quality assurance. Such characterization can be challenging for products in prefilled ...

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Rheology masterclass 1 - The basic of viscosity

Rheology is defined as the science of deformation and flow and in particular refers to materials that show viscoelastic or non-Newtonian behaviour when stressed. Such materials include suspensions, emulsions, polymer solutions and foams to name but a few.Part 1 of this two part webinar series ...

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Application of particle size analysis in Oral Solid Dose product formulation

The development of oral solid dose (OSD) products requires a knowledge of how the physical properties of the excipients and active pharmaceutical ingredients (APIs) present within a formulation affect product performance. This requires access to relevant technologies for measurement properties ...

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Forensic Analyses by Morphologically-Directed Raman Spectroscopy

Morphologically-Directed Raman Spectroscopy (MDRS) can be applied to a variety of forensic evidence types such as illicit drugs, counterfeit pharmaceuticals, hoax powders, soils and gunshot residues. It is a novel and reliable tool that enables criminalists to obtain more information from ...

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Making squeeze flow measurements on a rotational rheometer

Squeeze flow rheometry involves compressing a material between two parallel plates in order to determine its rheological properties. Squeeze flow measurements can be made with a rotational rheometer having suitable axial capabilities (normal force and gap control) such as Kinexus and can offer ...

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History and development of Malvern GPC Viscometers

Gel Permeation Chromatography (GPC), also known as Size Exclusion Chromatography (SEC), is a very popular analytical toll for characterizing natural and synthetic polymers. The introduction of the first differential Viscometer (Viscotek Model H100) back in the early 1980's provided a quantum leap ...

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The mathematics of image analysis

Thresholding, dilation, erosion, reporting - these are some of the terms used in image analysis. We'll explain some of the mathematics used in converting an image into size and shape information.

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