
UHPLC systems: Nexera XS inert
Inert UHPLC for Enhanced Sensitivity and Selectivity in Chromatography of Biomolecules
Shimadzu Deutschland GmbH
The fully inert flowline prohibits analyte adsorption for best separation and reliable results
Online pH-monitoring for accurate mobile phase control and highly reproducible chromatography
Full data integrity by integration of all modules into the software and audit trail








Bioinert UHPLC with corrosion-resistant flowline and pH-monitoring for best biomolecule analysis
The Nexera XS inert system offers ideal conditions for the separation of biomolecules, by combining the elevated pressure tolerance of a UHPLC system with complete inertness of the sample flow path. This is ensured by the absence of wetted metal surfaces and offers ultra-high resistance to corrosion. In addition, the Nexera XS inert comprise user-friendly finger-tight, zero-dead-volume tubing connectors that withstand pressure up to 105 MPa for fast UHPLC analysis. Optional switching valves used for method scouting or trap-and-elute analysis are designed to inhibit metal adsorption. The also optional pHM-40 mobile phase monitor continuously tracks any changes in pH in real time, making the Nexera XS inert the ultimate tool for ion-exchange or size-exclusion chromatography, where mobile phase pH can strongly affect chromatographic separation. The portfolio is completed by a wide range of consumables (e.g., columns, vials) that feature unique technologies for inhibiting sample adsorption.

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The NEW Nexera XS inert

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The NEW online pH-monitor

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Hand-tight fittings of inert coated capillaries for up to 105 MPa

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User-friendly touch display for easy control of the UHPLC in the lab
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UHPLC systems: Nexera XS inert
Inert UHPLC for Enhanced Sensitivity and Selectivity in Chromatography of Biomolecules