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Rare earth orthoferrite LnFeO3 nanoparticles for bioimaging
06-Sep-2018
Magnetic resonance imaging (MRI) has emerged as one of the most powerful clinical imaging tools because of its superb spatial resolution and soft tissue contrast, especially when using contrast agents. In the European Journal of Inorganic Chemistry, scientists have presented a new kind of ...
Modulating photo- and electroluminescence in a stimuli-responsive molecular dye
17-Aug-2018
Controlling the excited electronic states in luminescent systems remains a challenge in the development of fluorescent and phosphorescent dyes. Now, scientists in Japan have developed a unique organic fluorophore that changes its emission color without loss of efficiency when externally ...
Triplex-signal chemosensor for naked eye and spectrometric lead detection
29-May-2018
Environmental lead exposure is one of the most significant public health threats worldwide. Consequently, reliable, quick, inexpensive, and easy-to-handle lead assays are urgently needed. Scientists have now presented a novel chemosensor for lead. It offers a triplex signal upon binding of lead ...
10-Feb-2017
Positron emission tomography plays a pivotal role for monitoring the distribution and accumulation of radiolabeled nanomaterials in living subjects. The radioactive metals are usually connected to the nanomaterial through an anchor, a so-called chelator, but this chemical binding can be omitted ...
Making light pulses ever-shorter is one of the goals in ultrafast optics.
04-Jun-2015
Ultrashort light pulses are a valuable achievement. They make it possible to observe chemical reactions, opening up the field of femtochemistry. Other current and/or future applications include high capacity telecommunications systems, photonic switching devices, optical coherence tomography, and ...
Practical approach for assessing the melanin and blood content of the skin
24-Apr-2015
Many factors can change skin pigmentation, including aging, exposure to UV light, certain drugs, as well as certain diseases. A simple technique for measuring skin pigmentation could be a helpful tool for research and diagnostics. The same goes for measuring the skin blood content. Alteration of ...
A new approach enables rapid characterization of living suspension cells in 4 dimensions
01-Apr-2015
Optical imaging of highly motile cells or cells in suspension, such as bacterial systems, yeast cells, and immune cells, is a challenging task, in many cases it is just not possible. The human immunodeficiency virus (HIV), for example, can spread very efficiently from an infected T cell to an ...
Flexible wide-field endoscope provides label-free contrast of tissue based on fluorescence lifetime imaging of tissue autofluorescence
11-Feb-2015
Fluorescence lifetime imaging (FLIM) of tissue autofluorescence has been shown to provide labelfree contrast between different types and states of tissue. Clinical FLIM can combine lifetime contrast with morphological information to provide a direct comparison between different spatial regions – ...
In vivo and non-invasive: Collagen remodeling after micro-ablative fractional laser resurfacing can be monitored by two-photon microscopy.
25-Nov-2014
Many people in the Western World consider it as a social need to hide the effects of aging. For this purpose, different cutaneous rejuvenation treatments have been developed, including a laser-based technique, known as laser resurfacing. Skin irradiation with high-power pulsed laser light induces ...
12-Dec-2013
Multimodal nonlinear microscopy has matured to a key imaging modalities in life science and biomedicine. It offers label-free visualization of tissue structure and chemical composition, high depth penetration, intrinsic 3D sectioning, diffraction limited resolution and low phototoxicity. In the ...