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"The exciting thing about this technology is that for the first time, we can see how the environment shapes cancer evolution"
11-Nov-2022
Researchers have created a tool that maps how breast cancer grows in previously unseen detail, and highlights how the cells around the tumour may be the key to controlling the spread of disease. The new technology can trace which populations of breast cancer cells are responsible for the spread ...
13-Nov-2014
Every year hundreds of thousands of people die from diarrhoeal diseases caused by ETEC bacteria. A study published in Nature Genetics describes how Swedish researchers have mapped the spread of strains of ETEC bacteria around the world. It provides key information about how pathogenic bacteria ...
Role of rare APOC3 variant in reducing triglyceride levels identified using UK10K data
18-Sep-2014
Research using data collected from around 4,000 healthy people in the UK has enabled scientists to identify a rare genetic variant that dramatically reduces levels of certain types of lipids in the blood. The study is the first to emerge from the UK10K Project's cohort of samples from the general ...
27-Aug-2013
Concealed within the vastness of the human genome, (comprised of some 3 billion base pairs), mutations are commonplace. While the majority of these appear to have neutral effect on human health, many others are associated with diseases and disease susceptibility. Reed Cartwright, a researcher at ...
New study will enable better antenatal diagnosis for sufferers of rare blood and skeletal disorder
28-Feb-2012
Researchers have identified an elusive gene responsible for Thrombocytopenia with Absent Radii (TAR), a rare inherited blood and skeletal disorder. As a result, this research is now being transformed into a medical test that allows prenatal diagnosis and genetic counselling in affected ...
Cornell plays key role in developing most detailed map of human DNA variation
03-Nov-2010
Cornell researchers are part of an international collaboration to build the most detailed map of human genetic variation. The map promises to provide a much more comprehensive understanding of the role of inherited DNA variation in human history, evolution and disease and the best methods to use ...
Uncovering Mutations Found in Deadly Transmissible Cancer Could Help Conservation Efforts
20-Sep-2010
Researchers from Illumina, Inc. and the Wellcome Trust Sanger Institute have used Illumina's next generation sequencing technology to create a draft genome sequence for the endangered Tasmanian devil, and will use this to find genetic mutations in the transmissible cancer that is ravaging its ...
21-Jul-2009
Scientists have sequenced the genome of the parasite that causes intestinal schistosomiasis (also known as bilharzia or snail fever), a devastating tropical disease that afflicts more than 200 million people in the developing world. Najib El-Sayed, associate professor in the University of ...
Interactions between proteins studied on a global scale
25-Feb-2008
Wellcome Trust Sanger Institute scientists have developed a new large-scale method to identify the interactions between proteins that are a major target for therapeutic intervention. The novel method can identify the weak, short-lived interactions that are characteristic of cell responses to cues ...
