New Molecular Microscopy Uncovers how Breast Cancer Spreads

"The exciting thing about this technology is that for the first time, we can see how the environment shapes cancer evolution"

11-Nov-2022 - Researchers have created a tool that maps how breast cancer grows in previously unseen detail, and highlights how the cells around the tumour may be the key to controlling the spread of disease. The new technology can trace which populations of breast cancer cells are responsible for the spread ...

Gene variant that dramatically reduces 'bad' lipids

Role of rare APOC3 variant in reducing triglyceride levels identified using UK10K data

18-Sep-2014 - Research using data collected from around 4,000 healthy people in the UK has enabled scientists to identify a rare genetic variant that dramatically reduces levels of certain types of lipids in the blood. The study is the first to emerge from the UK10K Project's cohort of samples from the general ...

New tool enhances the search for genetic mutations

27-Aug-2013 - Concealed within the vastness of the human genome, (comprised of some 3 billion base pairs), mutations are commonplace. While the majority of these appear to have neutral effect on human health, many others are associated with diseases and disease susceptibility. Reed Cartwright, a researcher at ...

Elusive platelet count and limb development gene discovered

New study will enable better antenatal diagnosis for sufferers of rare blood and skeletal disorder

28-Feb-2012 - Researchers have identified an elusive gene responsible for Thrombocytopenia with Absent Radii (TAR), a rare inherited blood and skeletal disorder. As a result, this research is now being transformed into a medical test that allows prenatal diagnosis and genetic counselling in affected ...

Cornell: Project aims to sequence 2,500 genomes

Cornell plays key role in developing most detailed map of human DNA variation

03-Nov-2010 - Cornell researchers are part of an international collaboration to build the most detailed map of human genetic variation. The map promises to provide a much more comprehensive understanding of the role of inherited DNA variation in human history, evolution and disease and the best methods to use ...

Illumina and Wellcome Trust Sanger Institute Announce Completed Genome for Endangered Tasmanian Devil

Uncovering Mutations Found in Deadly Transmissible Cancer Could Help Conservation Efforts

20-Sep-2010 - Researchers from Illumina, Inc. and the Wellcome Trust Sanger Institute have used Illumina's next generation sequencing technology to create a draft genome sequence for the endangered Tasmanian devil, and will use this to find genetic mutations in the transmissible cancer that is ravaging its ...

Scientists decode genome of deadly parasitic worm

21-Jul-2009 - Scientists have sequenced the genome of the parasite that causes intestinal schistosomiasis (also known as bilharzia or snail fever), a devastating tropical disease that afflicts more than 200 million people in the developing world. Najib El-Sayed, associate professor in the University of ...

Novel method to reveal drug targets

Interactions between proteins studied on a global scale

25-Feb-2008 - Wellcome Trust Sanger Institute scientists have developed a new large-scale method to identify the interactions between proteins that are a major target for therapeutic intervention. The novel method can identify the weak, short-lived interactions that are characteristic of cell responses to cues ...