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Machine learning assisted structure analysis reveals SARS-CoV-2 virus tactics

The proteins of Covid-19

17-Sep-2021

The proteins of SARS-CoV-2 play key roles in how the virus manages to evade immune defense and replicate itself in patients’ cells. An international research team – with significant contribution from the Technical University of Munich (TUM) – has now compiled the most detailed view of the virus' ...

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Messengers from gut to brain

Seen for the first time: T cells traveling from the gut and skin to the central nervous system

09-Sep-2021

Scientists have long been aware of a link between the gut microbiome and the central nervous system (CNS). Until now, however, the immune cells that move from the gut into the CNS and thus the brain had not been identified. A team of researchers in Munich has now succeeded in using violet light ...

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Taking aim at skin bacteria

Enzyme treatment of skin samples improves microbiome analysis

13-Aug-2021

Healthy skin has a bacterial shield to protect against germs: the microbiome. This complex assembly of microorganisms was previously believed to be difficult to decipher. A team of researchers has now succeeded in using the enzyme benzonase to identify the living bacteria in skin swabs through ...

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Versatile and reliable SARS-CoV-2 antibody assay

Automated microarray rapid test for detecting SARS-CoV-2 antibodies

28-Jun-2021

During the continued progression of the Corona pandemic, rapid, inexpensive, and reliable tests will become increasingly important to determine whether people have the associated antibodies – either through infection or vaccination. Researchers at the Technical University of Munich (TUM) have now ...

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The Cut and Restore Protein Trick: Self-Excising Designer Proteins Report Isoform Expression

07-Jun-2021

Our proteome is much bigger than our genome because one gene produces several variants of proteins called protein isoforms, whose disbalance is implicated in many diseases. A new bioengineered reporter system developed at Helmholtz Zentrum München and the Technical University of Munich now allows ...

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Chickens and pigs with integrated genetic scissors

Genome editing in farm animals

22-Apr-2021

Genetically engineered animals provide important insights into the molecular basis of health and disease. Research has focused mainly on genetically modified mice, although other species, such as pigs, are more similar to human physiology. Researchers at the Technical University of Munich (TUM) ...

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A multidimensional view of the coronavirus

Covid-19: analysis of protein interactions as a route to new drugs

20-Apr-2021

What exactly happens when the corona virus SARS-CoV-2 infects a cell? In an article published in Nature, a team from the Technical University of Munich (TUM) and the Max Planck Institute of Biochemistry paints a comprehensive picture of the viral infection process. For the first time, the ...

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A memory without a brain

How a single cell slime mold makes smart decisions without a central nervous system

25-Feb-2021

Having a memory of past events enables us to take smarter decisions about the future. Researchers at the Max-Planck Institute for Dynamics and Self-Organization (MPI-DS) and the Technical University of Munich (TUM) have now identified how the slime mold Physarum polycephalum saves memories – ...

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Quick look under the skin

Self-learning algorithms analyze medical imaging data

05-Jan-2021

Imaging techniques enable a detailed look inside an organism. But interpreting the data is time-consuming and requires a great deal of experience. Artificial neural networks open up new possibilities: They require just seconds to interpret whole-body scans of mice and to segment and depict the ...

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World’s first fingertip-mounted sensor that maintains user’s sensitivity

Ultrathin nanomesh sensor to measure sense of touch

25-Nov-2020

Scientists from the Technical University of Munich (TUM) and the University of Tokyo have developed an ultrathin pressure sensor that can be attached directly to the skin. It can measure how fingers interact with objects to produce valuable data for technological or medical applications. The ...

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