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RNA: A new method to discover its high-resolution structure

New research combines experimental data and molecular dynamics simulations to study biomolecules in their natural environment

16-Jun-2021

The structure of a biomolecule can reveal much about its functioning and interaction with the surrounding environment. The double-helical structure of DNA and its implications for the processes of transmission of genetic information form an obvious example. In a new study by SISSA - Scuola ...

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How to separate nanoparticles by “shape”

New strategy to separate molecules

13-Jun-2019

In our daily lives, the purpose and function of an item is defined by either its material, e.g. a rain jacket is fabricated of water-proof material, or its shape, e.g. a wheel is round to enable a rolling motion. What is the impact of the two factors on the nanoscale? The impact of material, ...

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It is easier for a DNA knot...

30-Mar-2017

Anyone who has been on a sailing boat knows that tying a knot is the best way to secure a rope to a hook and prevent its slippage. The same applies to sewing threads where knots are introduced to prevent them slipping through two pieces of fabric. How, then, can long DNA filaments, which have ...

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The large-scale stability of chromosomes

30-Jun-2016

"Interphase" refers to the period in the cell cycle in which chromosomes spend most of their time. During this phase, in between mitoses, chromosomes live "dissolved'' in the nucleus where they carry out the processes required for the duplication of genetic material. Our current knowledge ...

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The quantum dance of oxygen

Proposal for a new phase of the element, where atoms dance in quartets

09-Jul-2014

Perhaps not everyone knows that oxygen has– quite unusually for such a simple molecule – magnetic properties. The phase diagram of solid oxygen at low temperatures and high pressures shows, however, several irregularities (for example, proper "information gaps" with regard to these magnetic ...

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RIKEN and SISSA develop new biological analysis methods

18-Jun-2010

Researchers in Japan and Italy have developed new methods for biological analysis with dramatically higher sensitivity and detail than earlier techniques, expanding our understanding of RNA and its function in the cell. Described in Nature Methods, the methods open the door to the study of ...

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