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New method provides more precise information on types of leukaemia

Optical genome mapping could become a component of routine diagnostics

21-Feb-2022

In the characterization of leukaemias, also known as blood cancers, genetic analyses are crucial and provide information for the optimal treatment strategy. A research team from Bochum and Essen has used a new method that offers greater accuracy in this process. The so-called optical genome ...

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Catalyst surface analysed at atomic resolution

Particles observed during the catalysis process

12-Jan-2022

Catalyst surfaces have rarely been imaged in such detail before. And yet, every single atom can play a decisive role in catalytic activity. A German-Chinese research team has visualised the three-dimensional structure of the surface of catalyst nanoparticles at atomic resolution. This structure ...

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Reverse optogenetic tool developed

29-Jul-2021

Researchers at the Ruhr-Universität Bochum (RUB) have developed a new optogenetic tool, i.e. a protein that can be controlled in the living organism with light. They used an opsin - a protein found in the brain and eyes - from zebrafish and introduced it into the brains of mice. Unlike other ...

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What happens in brain cells affected by Alzheimer’s disease?

Studies on tissue from patients and mini-brains made from stem cells shed light on the disease

15-Jun-2021

In addition to plaques that accumulate outside of nerve cells in the brain, Alzheimer’s disease is also characterised by changes inside these cells. Researchers from the Cell Signalling research group at the Chair of Molecular Biochemistry at RUB, headed by Dr. Thorsten Müller, have been studying ...

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Quickly identify high-performance multi-element catalysts

Complex solid solution electrocatalyst discovery by computational prediction and high‐throughput experimentation

18-Feb-2021

Finding the best material composition among thousands of possibilities is like looking for a needle in a haystack. An international team is combining computer simulations and high-throughput experiments to do this. Catalysts consisting of at least five chemical elements could be the key to ...

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A prognostic Alzheimer’s disease blood test in the symptom-free stage

Memory deficit is a normal side effect of aging. At what point does memory loss become pathological?

08-Jan-2021

Using a blood test, a German-Dutch research team has predicted the risk of Alzheimer’s disease in people who were clinically diagnosed as not having Alzheimer’s disease but who perceived themselves as cognitively impaired (Subjective Cognitive Declined, SCD). The researchers analyzed blood ...

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Catalytic activity of individual cobalt oxide nanoparticles determined

Using a robotic arm

16-Dec-2020

Analyzing nanoparticles individually is a challenge precisely because they are so small. A new technique using electron microscopy and a robotic arm could make the process much easier. Precious metal-free nanoparticles could serve as powerful catalysts in the future, for example for hydrogen ...

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Detecting bacteria with fluorescent nanosensors

Luminous carbon nanotubes detect pathogens – and are quick and easy to use

26-Nov-2020

Researchers from Bochum, Göttingen, Duisburg and Cologne have developed a new method for detecting bacteria and infections. They use fluorescent nanosensors to track down pathogens faster and more easily than with established methods. A team headed by Professor Sebastian Kruß, formerly at ...

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Measuring pH locally with terahertz spectroscopy

New method to determine a local pH value near a specific site of a biomolecule

24-Nov-2020

Nowadays, it is easy to determine an average pH for larger quantities of liquid. It is a challenge, however, to define a local pH value. Researchers at Ruhr-Universität Bochum have developed a new method to determine a local pH value near a specific site of a biomolecule. A reliable measurement ...

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Attacking tumours directly on identification

Therapy and diagnostics of tumours in only one step is possible with the aid of so-called theranostic agents

04-Sep-2020

The combination of a biomolecule and a metal complex can target, bind, mark and damage cancer cells. A German-Spanish team has manufactured such a theranostic agent that visualises tumour cells by irradiation with visible light, and proved its effectiveness against lung cancer cells. Andres ...

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