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Therapeutic screening for Alzheimer’s disease

05-Dec-2013

Scientists in Canada and the United States have developed a chip sensor for monitoring how drug candidates alter amyloid-β peptide aggregation that they hope could be used to find new treatments for Alzheimer’s disease. Research into Alzheimer’s disease has shown that the self-aggregation of the ...

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Moving the MRI goalposts

28-Nov-2013

Scientists in the UK have developed a new class of MRI (magnetic resonance imaging) agents that promise to deliver clearer images more quickly. Chemical shifts from proton NMR normally fall between 0-12ppm, but water and fat resonate at 4.7 and 1.3ppm respectively, causing noise that can overlap ...

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High-throughput drug screening in 3D

06-Nov-2013

Scientists in China have developed a simple microchip that enables quick and inexpensive high-throughput screening of potential drug candidates in 3D cell cultures. Scientists often use cell-based high-throughput screening in the first stage of drug design as a technique to quickly identify the ...

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Detecting bacteria on paper

30-Oct-2013

Scientists in Canada have developed a low-cost, portable, paper-based device for detecting antibiotic-resistant bacteria that could be used in the field in remote areas to characterise infectious diseases and assess food and water quality. The scientists used a paper support to hold wax-patterned ...

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Monitoring kidney disease on a smart phone

17-Sep-2013

Researchers in the United States have developed a hand-held ‘albumin tester’ integrated with a smart phone for diagnosing and monitoring kidney disease. The lightweight device measures albumin levels in urine. The system, which could be used by kidney disease patients at home, integrates an ...

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A look behind Dalí’s paintings

17-Sep-2013

A collaboration of scientists, conservators and curators has developed a technique for assessing the condition of works of art without the need to remove samples from them, and used it to analyse a valuable collection of paintings by the enigmatic artist Salvador Dalí. Paintings undergo little ...

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Biomarkers can identify ethnicity at the crime scene

17-Sep-2013

A team of scientists in the United States and Germany have developed a biocatalytic assay that can rapidly identify ethnic origin from body fluid samples on-site at the crime scene. Methods for profiling samples from biological samples taken from crime scenes, such as DNA/RNA analysis, are ...

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Hydrazine has nowhere to hide

29-Aug-2013

Scientists in the US and Korea have developed a highly sensitive fluorescent probe that can detect a toxic chemical used in industrial processes in a variety of different environments – including living cells. Hydrazine is used in in many different applications – as the gas-forming agent in air ...

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Raman keeps lipstick evidence in the bag

14-Aug-2013

Scientists at the University of Kent, UK have used Raman spectroscopy to identify different types and brands of lipstick on crime scene evidence without having to remove it from the evidence bag. Lipstick marks can link someone to a crime scene and can be crucial for establishing physical contact ...

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Detecting efficient chiral compound catalysts

23-Jul-2013

Scientists in the United States have developed a sensor that could be used to help develop more efficient catalysts for producing chiral compounds in industry. In research they describe the preparation of inexpensive palladium complexes that provide a sensitive UV signal in the presence of some ...

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