50 Current news of LMU
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The interpretation of certain brain scans needs rethinking
15-Oct-2021
At the beginning of neurodegenerative disease, the immune cells of the brain – the “microglia” – take up glucose, a sugar molecule, to a much greater extent than hitherto assumed. Studies by the DZNE, the LMU München and the LMU Klinikum München, published in the journal Science Translational ...
New method to determine location and size changes of unlabeled proteins on membranes via their mass
06-Oct-2021
A large proportion of biologically relevant processes take place at membranes. Studying the dynamics of these processes in real time and without disturbing the biological system is still a major methodological challenge. A team led by Petra Schwille, director at the MPI of Biochemistry (MPIB), ...
Monitoring health and detect disorders at an early stage
11-Mar-2021
A new study carried out by a team of laser physicists, molecular biologists and physicians based at LMU Munich and the Max Planck Institute for Quantum Optics has confirmed the temporal stability of the molecular composition of blood in a population of healthy individuals. The data provide a ...
Researchers show that the light emitted by a single molecule can be detected with a low-cost optical setup. Their prototype could facilitate medical diagnostics
17-Feb-2021
Biomarkers play a central role in the diagnosis of disease and assessment of its course. Among the markers now in use are genes, proteins, hormones, lipids and other classes of molecules. Biomarkers can be found in the blood, in cerebrospinal fluid, urine and various types of tissues, but most of ...
Researchers simplify the MINFLUX microscope and have succeeded in differentiating molecules that are extremely close together and tracking their dynamics.
21-Jan-2021
Only a few years ago, an ostensibly fundamental resolution limit in optical microscopy was superseded - a breakthrough which in 2014 led to the Nobel Prize in Chemistry for super-resolution microscopy. Since then, there has been another quantum leap in this area, which has further reduced the ...
Watching metamaterials at work in real time using ultrafast electron diffraction
26-Nov-2020
Physicists from the University of Konstanz, Ludwig-Maximilians-Universität München (LMU Munich) and the University of Regensburg have successfully demonstrated that ultrashort electron pulses experience a quantum mechanical phase shift through their interaction with light waves in nanophotonic ...
Simple method to detect unintended alterations in the target gene itself – results indicate that such on-target events occur at high frequency
28-May-2020
CRISPR-Cas9 can alter genes at pre-defined sites in specific ways, but it does not always act as planned. An LMU team has now developed a simple method to detect unintended ‘on-target’ events, and shown that they often occur in human stem cells. The gene-editing system CRISPR-Cas9 has ...
02-Apr-2020
The interaction between biotin and streptavidin is a well-established experimental tool in bionanotechnology. LMU physicists have now shown that the mechanical stability of the complex is dependent on the precise geometry of the interface. Mechanical forces play a vital role at all levels in ...
02-Mar-2020
Biomedical researchers at LMU have isolated immune cells from human tonsils obtained following routine surgery, and used them to analyze aspects of the immune response and test the effects of anti-inflammatory agents at the cellular level. Human tissues that have been surgically removed from ...
New gene correction therapy
30-Jan-2020
Duchenne type muscular dystrophy (DMD) is the most common hereditary muscular disease among children. A Munich based team has developed a gene therapy that may provide permanent relief for those suffering from DMD. LMU researcher Eckhard Wolf was involved in the study. Muscles need dystrophin in ...
