New contrast mechanism improves xenon MRI

Enhanced speed, contrast, and information

14-Jan-2021 - Xenon magnetic resonance imaging offers deep insights into the human body and opens up new possibilities in the diagnosis and treatment of diseases. Physicists from the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) in Berlin have now achieved a considerable improvement of the ...

Light shed on the atomic resolution structure of phage DNA tube

A methodological milestone

17-Nov-2020 - Given that phages are able to destroy bacteria, they are of particular interest to science. Basic researchers from the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) in Berlin are especially interested in the tube used by phages to implant their DNA into bacteria. In collaboration ...

Determining the atomic structure of natural products more rapidly and accurately

23-Jan-2020 - Many drugs are derived from natural products. But before natural products can be exploited, chemists must first determine their structure and stereochemistry. This can be a major challenge, particularly when the molecules cannot be crystallized and contain only few hydrogen atoms. A new NMR-based ...

Dynamic images show rhomboid protease in action

01-Nov-2019 - Rhomboid proteases are clinically relevant membrane proteins that play a key role in various diseases. Using solid-state NMR spectroscopy, researchers from Berlin’s Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) have now been able to watch rhomboid proteases in a native lipid ...

Bringing cancer medication safely to its destination

12-Aug-2019 - Treating cancer more selectively and more effectively – this could be achieved with an innovative technology developed by teams of researchers at the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) and the Ludwig-Maximilians-Universität München (LMU). The process transforms proteins ...

More sensitive MRI diagnostics thanks to innovative “elastic” contrast media

04-Dec-2018 - Researchers from the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) have found a new method for obtaining high-quality images in magnetic resonance imaging (MRI), that requires less contrast medium compared to current methods. It is made possible by using an “elastic” protein ...