20 Current news of Karolinska Institutet

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New tool reveals function of enigmatic gene sequences

Study may eventually contribute to the development of new, targeted drugs

09-Mar-2022

While the large proportion of our genome that does not instruct our cells to form proteins has been harder to study than protein-coding genes, it has been shown to have vital physiological functions. Scientists at Karolinska Institutet in Sweden have now developed new high-precision tools able to ...

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New group of antibacterial molecules identified

International research group discovers promising scaffold for antimicrobial agents

19-Nov-2021

Researchers at Karolinska Institutet, Umeå University, and the University of Bonn have identified a new group of molecules that have an antibacterial effect against many antibiotic-resistant bacteria. Since the properties of the molecules can easily be altered chemically, the hope is to develop ...

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New insight into cell receptors opens the way for tailored cancer drugs

12-Feb-2019

New research on how cancer mutations influence a certain type of receptor on the cell membrane opens the way for the development of tailored drugs for certain cancers, such as rectal cancer and lung cancer. This according to researchers at Sweden's Karolinska Institutet and Uppsala University, ...

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Nobel Prize for Physiology or Medicine 2018 Announced

Appreciation of the research on cancer therapies

01-Oct-2018

The researchersJames P. Allison and Tasuku Honjo were announced today as this year's winners of the Nobel Prize for Physiology or Medicine. Their achievements in the field of cancer therapy was groundbreaking and worthy of the Nobel Prize Committee's appreciation. With the help of the immune ...

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The Nobel Prize Winners 2017

Internal clock, gravitational waves and cold analysis

04-Oct-2017

This year's Nobel Prizes were awarded to a total of nine scientists. The research areas that have been awarded and the prize winners at a glance: Nobel Prize for Physiology or Medicine The Nobel Committee at the Karolinska Institute has awarded the Nobel Prize in Physiology or Medicine to the ...

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Revealing the molecular mechanisms of the circadian clock

Nobel Prizes in Physiology or Medicine announced

02-Oct-2017

Life on Earth is adapted to the rotation of our planet. For many years we have known that living organisms, including humans, have an internal, biological clock that helps them anticipate and adapt to the regular rhythm of the day. But how does this clock actually work? Jeffrey C. Hall, Michael ...

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New nanoparticle technology to decipher structure and function of membrane proteins

10-Mar-2016

Researchers at Karolinska Institutet, Sweden, have developed a nanoparticle technology that can be used to stabilise membrane proteins so that their structure can be studied in a lipid environment. The method makes it possible to access drug targets that previously could not be investigated and ...

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Technological breakthrough paves the way for better drugs

08-Jul-2013

Researchers at Karolinska Institutet in Sweden have developed the first method for directly measuring the extent to which drugs reach their targets in the cell. The method could make a significant contribution to the development of new, improved drug substances. Most drugs operate by binding to ...

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Learning the alphabet of gene control

24-Jan-2013

Scientists at Karolinska Institutet in Sweden have made a large step towards the understanding of how human genes are regulated. In a new study they identified the DNA sequences that bind to over four hundred proteins that control expression of genes. This knowledge is required to understand how ...

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A better way to count molecules discovered

22-Nov-2011

Researchers at the Swedish medical university Karolinska Institutet have developed a new method for counting molecules. Quantifying the amounts of different kinds of RNA and DNA molecules is a fundamental task in molecular biology as these molecules store and transfer the genetic information in ...

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