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How Cells Feel Curvature

Scientists find mechanism that allows cells to sense the curvature of tissue around them

22-Nov-2021

Cells in your body cannot see, but they can feel their surroundings and their own shape. Scientists at the University of Mons and the Institute of Science and Technology (IST) Austria now showed via both - experiments and theory - how cells can sense the curvature of tissue around them and how ...

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Frozen: Cutting-edge technology reveals structures within cells

05-Jan-2021

New methods enable scientists at IST Austria to take a look at the innermost of cells: high-resolution images of deep-frozen cells show structures that previously could only be guessed at. Temperatures of minus 196 degrees Celsius enable high-resolution imaging of the cell’s interior. Researchers ...

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Structure of ATPase, the world’s smallest turbine, solved

Location of the permeability transition pore found

17-Sep-2020

The chemical ATP, adenosine triphosphate, is the fuel that powers all life. ATP is found in all known forms of life, where it provides energy to drive muscle contraction, impulse propagation and chemical synthesis. Despite ATP’s central role, the structure of the enzyme generating ATP, F1Fo-ATP ...

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Structure of protein nano turbine revealed

Scientists determine the first structure of a cell’s rotary engine using state-of-art microscopy

02-Sep-2019

Cells rely on protein complexes known as ATP synthases or ATPases for their energy needs – adenosine triphosphate (ATP) molecules power most of the processes sustaining life. Structural biologist Professor Leonid Sazanov and his research group from the Institute of Science and Technology Austria ...

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High-end microscopy reveals structure and function of crucial metabolic enzyme

30-Aug-2019

The enzyme transhydrogenase plays a central role in regulating metabolic processes in animals and humans alike. Malfunction can lead to serious disorders. For the first time, structural biologists at the Institute of Science and Technology Austria (IST Austria) have now visualized and analyzed ...

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How neurons and glia cells are created in the developing brain

08-May-2017

Neurons and glia are the cells that make up our brain. In the cortex, the brain area that enables us to think, speak and be conscious, neurons and most glia are produced by a type of neural stem cell, called radial glia progenitors (RGPs). It is vital that no errors occur in this process as ...

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