15 Current news of European Molecular Biology Laboratory

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How deadly parasites ‘glide’ into human cells


X-ray analysis reveals structure of molecular machinery of malaria and toxoplasmosis pathogens

03-Nov-2020

An investigation at DESY's X-ray source PETRA III provides new insights into the molecular machinery by which certain parasites travel through the human organism. The study, led by Christian Löw from the Hamburg branch of the European Molecular Biology Laboratory EMBL, analyzed the so-called ...

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Happy hour for time-resolved crystallography

Researchers simplify time-resolved X-ray crystallography

19-Sep-2019

Researchers from the Department of Atomically Resolved Dynamics of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science in Hamburg, the University of Hamburg and the European Molecular Biology Laboratory (EMBL) outstation in the ...

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Toxin responsible for Legionella growth identified

24-Jul-2019

A team of scientists led by EMBL group leader Sagar Bhogaraju and Ivan Dikic of Goethe University, Frankfurt, discovered that the toxin SidJ in Legionella bacteria enforces a unique modification on human proteins and helps legionella grow inside human cells. SidJ hijacks human protein Calmodulin ...

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New Ways to Look at Protein-RNA Networks

10-Dec-2018

For their vital tasks, all RNA molecules in our cells require proteins as binding partners. Scientists at the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) and colleagues from the European Molecular Biology Laboratory (EMBL) have developed the first method with which they ...

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Detailed structure of cell’s garbage disposal unit reveals surprise in how it is targeted by cancer drugs

Every atom counts

08-Aug-2016

Malignant cancer cells not only proliferate faster than most healthy cells in our bodies. They also generate more “junk”, such as faulty and damaged proteins. This makes cancer cells inherently more dependent on the most important cellular garbage disposal unit, the proteasome, which degrades ...

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Scientists X-ray protein crystals inside cells

Novel approach to unveil the structure of challenging biomolecules

22-Jan-2016

Scientists from the European Molecular Biology Laboratory EMBL have teamed up with experts from DESY and the U.S. SLAC National Accelerator Laboratory to X-ray protein crystals naturally produced within biological cells. The study at the world's currently most powerful X-ray laser LCLS at SLAC ...

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Lighting the way

16-Oct-2015

A microscopy technique is poised to shine new light on biological questions: as sheets of light can scan everything from developing embryos to single cells or functioning brains, a technique called light-sheet microscopy is gaining traction. It enables scientists to observe living cells in three ...

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Three-dimensional model of bacterium

New methods of electron microscopy decode the structure of Gemmata obscuriglobus

16-Aug-2013

Certain bacteria can build such complex membrane structures that, in terms of complexity and dynamics, look like eukaryotes, i.e., organisms with a distinct membrane-bound nucleus. Scientists from Heidelberg University and the European Molecular Biology Laboratory (EMBL) made this discovery ...

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Small code change, big effect

Using synthetic biology to precisely label proteins

28-Mar-2011

Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have developed a new method which enables researchers to label any protein of their choice with any of a wide variety of previously available compounds, in living cells, by introducing a single reactive ...

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How cells export and embed proteins in the membrane

EMBL scientists first to visualise crucial step

16-Dec-2010

Like an overprotective parent on the first day of school, a targeting factor sometimes needs a little push to let go of its cargo. Scientists at the European Molecular Biology Laboratory (EMBL) in Grenoble, France, have visualised one such hand-over. They were the first to determine the structure ...

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