Researchers develop new approach to discover pervasive ‘forever’ chemicals known as PFAS

Advanced mass spectrometry helps unravel complexity of PFAS chemistry

07-Feb-2022 - PFAS, a family of thousands of human-made chemicals, are everywhere, and some of them are known to be harmful for our bodies and the environment. Even more frightening is how little we know about these pervasive pollutants found in everything from food packaging and cleaning products to ...

It's not an antibody, it's a frankenbody: A new tool for live-cell imaging

Antibody-based probe works in living systems and targets the classic HA tag

05-Jul-2019 - Antibodies are the biomolecules our immune systems deploy to find, tag and destroy invading pathogens. They work by binding to specific targets, called epitopes, on the surfaces of antigens - like locks to keys. For many decades, scientists have cleverly exploited this selective tagging mechanism ...

Dynamics of key viral attack strategy visible for first time

Visualizing and quantifying frameshifting mechanisms in living cells

11-Jun-2019 - Many infectious viruses, from HIV to West Nile, rely on a fundamental biological process called frameshifting to maximize their attack. Long identified as a key mechanism that viruses use to proliferate inside their hosts, the real-time dynamics of frameshifting had never been directly observed, ...

A traffic cop for the cell surface

Researchers illuminate a basic biological process

01-Mar-2017 - On the surfaces of our trillions of cells is a complex crowd of molecules moving around, talking to each other, occasionally segregating themselves, and triggering basic functions ranging from pain sensation to insulin release. The structures that organize this microscopic traffic jam are no ...

Beating the limits of the light microscope, one photon at a time

30-May-2016 - The world's most advanced light microscopes allow us to see single molecules, proteins, viruses and other very small biological structures. But even the best microscopes have their limits. Colorado State University scientists are pushing the limits of a technique called super-resolution ...