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Simplified screening of individual bacterial species in biosamples

Method saves time and costs when analysing complex microbiological samples

30-Mar-2023

In medical research and diagnostics, the microbiome, i.e. the microbial colonisation of the intestine, is increasingly gaining attention. A stool sample can be used to precisely analyse the complex microbial ecosystem of the gut. There are basically two methods for this: traditional cultivation ...

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Detecting pollutants at ultra-trace levels

Material scientists develop nano-structured and reusable substrate for ultra-sensitive detection of low-concentration analytes - Spin-off planned

29-Mar-2023

Surface-Enhanced Raman Scattering (or Spectroscopy), known as SERS, is an advanced analysis method that extends the range of Raman applications to trace analysis such as part per million level detection of a pollutant in water or different liquids. SERS has a high potential to be used in the ...

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New analysis method developed for nano and quantum materials

Using electron microscopy to create ultrafast movies of nano-processes

27-Feb-2023

A slow-motion movie on sports television channels shows processes in hundredths of a second. By contrast, processes on the nanoscale take place in the so-called femtosecond range: For example, an electron needs only billionths of a second to orbit a hydrogen atom. Physicists around the world are ...

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Novel way to identify still unknown pathogens

Evolutionary trade-offs: Balancing genetic disease risks and pathogen protection

02-Feb-2023

Certain genes can exist in different, functionally divergent variants in the individuals of a species. If they lead to clear differences, for example in a phenotype or susceptibility to disease, this is known in biology as a polymorphism. Typical examples are a number of genes whose variants are ...

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Sharper than ever: Physicists make molecular vibrations more detectable

The new method will improve the understanding of interactions in molecular systems and to further develop simulation methods

22-Sep-2022

In molecules, the atoms vibrate with characteristic patterns and frequencies. Vibrations are therefore an important tool for studying molecules and molecular processes such as chemical reactions. Although scanning tunnelling microscopes can be used to image individual molecules, their vibrations ...

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Protection against COVID-19: experience is not always an advantage for the immune response

A good response to the SARS-CoV-2 vaccination is based on naive immune cells, whereas pre-existing memory cells are rather disadvantageous

16-Aug-2022

People who have often been infected by common cold viruses – which also belong to the coronaviruses – are not better protected against COVID-19, neither after infection with SARS-CoV-2 nor after vaccination. "We already showed in 2020 that earlier exposure to common cold viruses does not provide ...

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Breakthrough: Prospect of blood test for Parkinson’s disease for the first time

A new method reliably detects protein changes in blood that are typical of Parkinson's disease: "The results are really sensational"

22-Jun-2022

Until now, the diagnosis of Parkinson's disease has been based primarily on typical movement disorders such as muscle stiffness, slower movements and shaking. However, the disease starts up to twenty years before it becomes noticeable as a result of these symptoms. To date, there have been ...

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Previously unknown mode of bacterial growth discovered

Research teams use imaging and modelling to explain why single bacterial cells do not always grow exponentially

18-Nov-2021

Bacteria as unicellular organisms reproduce by dividing their entire organism. In this way, they can multiply particularly quickly, which allows the exponential growth of bacterial populations, also known from pathogens. The population growth is based on the growth of the individual bacterial ...

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Large genomic analysis highlights COVID-19 risk factors

An international collaboration uncovers several genetic markers associated with SARS-CoV-2 infection or COVID-19 severity

13-Jul-2021

In March of 2020, thousands of scientists around the world united to answer a pressing and complex question: what genetic factors influence why some COVID-19 patients develop severe, life-threatening disease requiring hospitalization, while others escape with mild symptoms or none at all? A ...

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Watching cell division live

Highest resolution insights into living cells

16-Apr-2021

Bacteria as unicellular organisms normally reproduce by binary cell division, i.e. the duplication of the entire organism consisting of a single cell. This allows particularly rapid multiplication, such as the exponential growth known from pathogens, and requires the separation and distribution ...

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