Innovative approach to cell binding could help our understanding of diseases

12-Aug-2022 - The ligand-receptor binding is important for biological processes such as immunity and infectious disease. For example, the leukocyte can enter injured tissue by binding to the P selectin on the endothelial cells. COVID-19 is caused by the binding between viral spikes and angiotensin-converting ...

Snapshot measurement of single nanostructure’s circular dichroism

29-Mar-2022 - The 3D conformation of a molecule or nanostructure determines its function. For instance, a left-handed amino acid can be beneficialtohealth, while its right-handed compartment can be toxic. With today’s optical imaging techniques, one can accurately locate a molecule or a nanostructure, but ...

Deep learning enables early detection and classification of live bacteria using holography

Development of an AI-powered smart imaging system for early-detection and classification of live bacteria in water samples

15-Jul-2020 - Waterborne diseases affect more than 2 billion people worldwide, causing substantial economic burden. For example, the treatment of waterborne diseases costs more than $2 billion annually in the United States alone, with 90 million cases recorded per year. Among waterborne pathogen-related ...

Plasmon-powered upconversion nanocrystals for enhanced bioimaging and polarized emission

23-May-2017 - Lanthanide-doped upconversion nanocrystals (UCNCs) have recently found great potential in the applications of near-infrared bioimaging and nonlinear optoelectronic devices due to their tunable spectral characteristics and excellent photostability. In particular, their near-infrared excitation ...

Dipole orientation: New dimension in super-resolution microscopy

09-Dec-2016 - Recently, a new polarization-dipole azimuth-based super-resolution technique has been proposed by a group of researchers in Peking University (China), Tsinghua University (China), and University of Technology Sydney (Australia). It not only provides a new dimension for super-resolution, but also ...