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Innovative approach to cell binding could help our understanding of diseases


The ligand-receptor binding is important for biological processes such as immunity and infectious disease. For example, the leukocyte can enter injured tissue by binding to the P selectin on the endothelial cells. COVID-19 is caused by the binding between viral spikes and angiotensin-converting ...


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Snapshot measurement of single nanostructure’s circular dichroism


The 3D conformation of a molecule or nanostructure determines its function. For instance, a left-handed amino acid can be beneficialtohealth, while its right-handed compartment can be toxic. With today’s optical imaging techniques, one can accurately locate a molecule or a nanostructure, but ...


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Deep learning enables early detection and classification of live bacteria using holography

Development of an AI-powered smart imaging system for early-detection and classification of live bacteria in water samples


Waterborne diseases affect more than 2 billion people worldwide, causing substantial economic burden. For example, the treatment of waterborne diseases costs more than $2 billion annually in the United States alone, with 90 million cases recorded per year. Among waterborne pathogen-related ...


Plasmon-powered upconversion nanocrystals for enhanced bioimaging and polarized emission


Lanthanide-doped upconversion nanocrystals (UCNCs) have recently found great potential in the applications of near-infrared bioimaging and nonlinear optoelectronic devices due to their tunable spectral characteristics and excellent photostability. In particular, their near-infrared excitation ...


Dipole orientation: New dimension in super-resolution microscopy


Recently, a new polarization-dipole azimuth-based super-resolution technique has been proposed by a group of researchers in Peking University (China), Tsinghua University (China), and University of Technology Sydney (Australia). It not only provides a new dimension for super-resolution, but also ...


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