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Researchers programmed a tool that accurately recognises and picks proteins in electron cryo-tomography, substituting troublesome hand selection
24-May-2023
Electron cryo-tomography (cryo-ET) is emerging as a powerful technique to provide detailed 3D images of cellular environments and enclosed biomolecules. However, one of the challenges of the methodology is the identification of protein molecules in the images for further processing. A research ...
Single-cell multi-omics reveals that cell types are differentially involved in the production and accumulation of medically relevant plant compounds
19-May-2023
In a new study published in Nature Chemical Biology, an international team of researchers from the University of Georgia, USA, and the Max Planck Institute for Chemical Ecology in Jena, Germany, presents a promising strategy for elucidating metabolic pathways for plant compounds of medicinal ...
In a highly transdisciplinary study, scientists are rebuilding microbial natural products up to 100,000 years old
08-May-2023
Breakthroughs in ancient genome reconstruction and biotechnology are now revealing the rich molecular secrets of Paleolithic microorganisms. In a new study published in Science, a transdisciplinary team of researchers led by the Leibniz Institute for Natural Product Research and Infection ...
Largest cellular proteomic study of yeast cells unlocks fundamental insights
03-May-2023
A proteome is the entirety of all active protein molecules present within an organism, a certain type of tissue, or a cell under specific conditions and at a certain time. Now, an international team of researchers led by members from Charité – Universitätsmedizin Berlin, the Francis Crick ...
02-May-2023
Thanks to great technological advances, the genetic material of living beings can now be sequenced at a rapid rate. Comparisons of genomes, whether of closely related or completely different species, reveal particularly interesting findings. In this way, information can be obtained on ...
25-Apr-2023
Max Planck and Harvard research teams develop DeMAG, a new method shared as an open-source web server (demag.org) to help interpret mutations in disease genes and improve clinical decision-making. Despite the increasing use of genomic sequencing in clinical practice, interpreting rare genetic ...
The genome of the smallest baleen whale provides insight into evolution and tumor resistance
24-Apr-2023
The pygmy right whale (Caperea marginata) is the smallest of all baleen whales although it can grow to six metres in length and weigh up to three tons. The species occurs circumpolar in the Antarctic waters of the Southern Hemisphere, and only a handful of sightings have been reported thus far. ...
21-Apr-2023
Plants that glow under ultraviolet (UV) light aren’t only a figment of science fiction TV and movies. Roots of a traditional medicine plant called the orange climber, or Toddalia asiatica, can fluoresce an ethereal blue hue. And now, researchers in ACS Central Science have identified two coumarin ...
Using AI to move the boundaries of microscopy
12-Apr-2023
Small proteins play a critical role in the regulation of immune response, inflammation and neurodegenerative diseases. In order to better detect and study them, scientists at the Max-Planck-Institute for the Science of Light and FAU have combined one of the most effective microscopy methods, ...
Researchers are developing a new method
06-Apr-2023
The human body contains more than 30 trillion cells. Until recently, the sheer number of cells in the organism meant that approaches to understanding human diseases and developmental processes based on the analysis of single cells were a futuristic vision. The development of new sequencing ...
