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Toxicity testing on the placenta and embryo

Detection substances that are harmful to the embryo at an early stage of drug development

23-Jul-2021

Researchers at ETH Zurich have developed a cell culture test to detect substances that are directly or indirectly harmful to embryos. Based on an existing test used for developing new drugs and chemicals, the augmented version is designed to help reduce the number of animal experiments. Drugs ...

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In vitro Zoo helps in understanding SARS-CoV-2

Rhesus macaques and cats as potential spillback reservoirs for SARS-CoV-2

21-Jul-2021

A team of researchers from the Institute for Infectious Diseases (IFIK) at the University of Bern and the Institute of Virology and Immunology (IVI) have used a unique collection of advanced cell culture models of cells lining the airways from various domesticated and wildlife animals to ...

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Microscopy Deep Learning Predicts Viral Infections

Automatic detection of virus-infected cells - solely on the fluorescence of the cell nucleus

23-Jun-2021

When viruses infect cells, changes in the cell nucleus occur, and these can be observed through fluorescence microscopy. Using fluoresence images from live cells, researchers at the University of Zurich have trained an artificial neural network to reliably recognize cells that are infected by ...

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What the new pangenome reveals about bovine genes

New genes and functionalities discovered

28-May-2021

When researchers at ETH Zurich compared the reference genomes between several breeds of domestic cattle and closely related wild cattle, they discovered genes with previously unknown functions. Modern genetic research often works with what are known as reference genomes. Such a genome comprises ...

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First commercial Quantum Microscope

Swiss start-up Qnami closes 4.0M CHF Series A financing round

14-May-2021

Qnami announced today the closing of a 4.0M CHF (4.4M USD) Series A financing round led by Venture Capital funds Runa Capital and SIT Capital, further supported by Seed Round investors Quantonation, Verve Ventures, ZKB Start-up Finance and the High-Tech Gründerfonds. The funds will support ...

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Biomarker Detects Severe COVID-19 Early On

SARS-CoV-2-specific immune signature deciphered

10-May-2021

Severe cases of COVID-19 can now be detected at an early stage. Researchers at the University of Zurich have identified the first biomarker that can reliably predict which patients will develop severe symptoms. This can help to improve the treatment of severe cases of COVID-19. Most people who ...

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The First Comprehensive Single-Cell Atlas of Human Teeth

The dental pulp and periodontium are susceptible to caries and periodontitis and contain stem cells that have great regenerative potential

29-Apr-2021

Researchers at the University Zurich have mapped the first complete atlas of single cells that make up the human teeth. Their research shows that the composition of human dental pulp and periodontium vary greatly. Their findings open up new avenues for cell-based dental therapeutic ...

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Uniquely sharp X-ray view

For the first time, it is possible to look inside materials with a resolution down to individual atoms

26-Apr-2021

Researchers at the Paul Scherrer Institute PSI have succeeded for the first time in looking inside materials using the method of transient grating spectroscopy with ultrafast X-rays at SwissFEL. The experiment at PSI is a milestone in observing processes in the world of atoms. The structures on ...

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Predicting success in therapy with individualized cancer models

Further step in the direction of individualized medicine

11-Mar-2021

Scientists at Urology Research Laboratory of the Department for BioMedical Research (DBMR), University of Bern and Urology Department of the Inselspital of Bern, have established organoid culture models from prostate tumor biopsies. These are small clusters of cells which can be used to test the ...

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Researchers create sophisticated lung-on-chip

A fully biodegradable life-sized air-blood-barrier

10-Feb-2021

In collaboration with clinical partners from the Inselspital, researchers from the ARTORG Center for Biomedical Research of the University of Bern have developed a second-generation lung-on-chip model with life-size dimension alveoli in a stretchable membrane, made of purely biological material. ...

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