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Determining the structure of a molecule with laser-induced electron diffraction

11-Mar-2021

Light microscopes have revolutionized our understanding of the microcosmos, but their resolution is limited to about 100 nanometers. To see how molecules bond, break, or change their structure, we need at least 1000 times better resolution. Laser induced electron diffraction (LIED) is a technique ...

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New technology to detect bitter almonds in real time

02-Feb-2021

Who hasn't at some point been chewing on an almond and tasted an unpleasant and unexpected aftertaste that has nothing to do with the taste we are used to from one of the most consumed nuts in the world? The culprit has a name: amygdalin, a diglucoside that, when in contact with enzymes present ...

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Epigenetics key to daily production of 10 billion blood cells without mistakes

Study reveals a gene key for blood cell specialisation

10-Aug-2020

Just one in 2,000 bone marrow cells are hematopoietic stem cells (HSC), but these are the source of the ten billion blood cells humans make every day. In a new study published, researchers from the Centre for Genomic Regulation (CRG), in Barcelona, show that the epigenetic regulator Phf19 is ...

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New depths in infrared nanospectroscopy

Subsurface chemical nanoidentification by nano-FTIR spectroscopy

31-Jul-2020

Researchers from the Nanooptics Group at CIC nanoGUNE (San Sebastian) demonstrate that nanoscale infrared imaging - which is established as a surface-sensitive technique - can be employed for chemical nanoidentification of materials that are located up to 100 nm below the surface. The results ...

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CRISPR-edited C. elegans identifies vulnerabilities in cancer

25-Oct-2019

At first glance, a one-millimeter worm that needs to be observed with a magnifying glass does not resemble a human being at all. However, the nematode Caenorhabditis elegans, an animal model widely used in biomedical research by hundreds of laboratories around the world, has approximately the ...

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Targeting a large family of parasites

Potential drug target is identified

23-Mar-2018

Apicomplexa form one of the largest and most diverse groups of obligate intracellular parasites, capable of infecting almost every kind of animal. It is estimated that between 1.2 and 10 million species exist, but only about 5,000-6,000 have been identified to date. These include Plasmodium (that ...

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Why are genetically identical individuals different? Ask your mum!

04-Dec-2017

Does the age of a mother influence the traits and characteristics of her progeny, and how? A team of scientists at the Centre for Genomic Regulation (CRG) in Barcelona have addressed these questions by studying tiny, genetically identical C. elegans worms. "Our lab has long been interested in ...

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Why can hot water freeze faster than cold water?

16-Nov-2017

The researchers have confirmed how this phenomenon occurs in granular fluids, that is, those composed of particles that are very small and interact among those that lose part of their kinetic energy. Thanks to this theoretical characterization, "we can simulate on a computer and make analytical ...

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A hybrid material to spot organic contaminants in the atmosphere

31-Jul-2017

The development of hybrid materials is an emerging field in materials science. As the researcher explained, the interest in these materials stems from "the success in combining that stability of inorganic components with the versatility of organic components. Blending them causes the properties ...

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State-of-the-art text mining technologies for chemistry

23-Jun-2017

The Biological Text Mining Unit at the Spanish National Cancer Research Centre (CNIO) together with with researchers at the Center for Applied Medical Research (CIMA), of the University of Navarra, in Pamplona, and the Barcelona Supercomputing Centre (BSC-CNS) have published the first exhaustive ...

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