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Researchers engineer cells to destroy malignant tumor cells but leave the rest alone

30-Jun-2021

Researchers at McMaster University have developed a promising new cancer immunotherapy that uses cancer-killing cells genetically engineered outside the body to find and destroy malignant tumors. The modified "natural killer" cells can differentiate between cancer cells and healthy cells that are ...

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It's snowing plastic

New technique detects minute particles of plastics in snow, rain and even soil

22-Mar-2021

The snow may be melting, but it is leaving pollution behind in the form of micro- and nano-plastics according to a McGill study that was recently published in Environmental Pollution. The pollution is largely due to the relatively soluble plastics found in antifreeze products (polyethylene ...

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New more powerful genome editing method

Scientists can now edit multiple genome fragments at a time

20-Mar-2020

Toronto scientists can now edit multiple sites in the genome at the same time to learn how different DNA stretches co-operate in health and disease. CRISPR-based DNA editing has revolutionized the study of the human genome by allowing precise deletion of any human gene to glean insights into its ...

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Improving research with more effective antibodies

Scientists demonstrate flaws in protein detection tools, and outline a solution

17-Oct-2019

A new study points to the need for better antibody validation, and outlines a process that other labs can use to make sure the antibodies they work with function properly. Antibodies are used in laboratories and clinics to study proteins, which are the biomolecules that translate information from ...

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Researchers create nano-bot to probe inside human cells

15-Mar-2019

University of Toronto Engineering researchers have built a set of magnetic 'tweezers' that can position a nano-scale bead inside a human cell in three dimensions with unprecedented precision. The nano-bot has already been used to study the properties of cancer cells, and could point the way ...

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Cross-species cancer comparison uncovers new drug targets

Drug targets for a form of melanoma from genetic mutations found in humans, dogs and horses

13-Feb-2019

New drug targets for a rare form of melanoma may result from the discovery of similar genetic mutations found in humans, dogs and horses under a first-ever tri-species DNA sequencing study involving a University of Guelph researcher. Melanoma is a cancer that most commonly occurs in the skin in ...

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The Secret Contamination of Polar Bears

Hundreds of unrecognized halogenated contaminants discovered in polar bear serum

05-Dec-2018

Using a new approach to measure chemical contaminants in polar bears, scientists from Canada and the United States found a large variety of new chlorinated and fluorinated substances, including many new polychlorinated biphenyl metabolites. Worryingly, these previously unrecognized contaminants ...

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Unraveling a genetic network linked to autism

06-Nov-2018

Donnelly Centre researchers have uncovered a genetic network linked to autism. The findings will facilitate developing new therapies for this common neurological disorder. As part of a collaborative research program focusing on autism led by Benjamin Blencowe, a professor in the University of ...

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Detecting hundreds of proteins in a single sample

Barcoding technique offers cost-effective alternative to current technology

17-Aug-2018

New technology developed by a team of McGill University scientists shows potential to streamline the analysis of proteins, offering a quick, high volume and cost-effective tool to hospitals and research labs alike. Proteins found in blood provide scientists and clinicians with key information on ...

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A DNA 'shield' with crucial roles in normal cell division

20-Jul-2018

In immune cells, this is crucial to make antibodies In cancer, mutations in complex could lead to resistance to BRCA-targeting PARP inhibitor drugs or platinum chemotherapies Scientists have made a major discovery about how cells repair broken strands of DNA that could have huge implications for ...

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