Scientists have reconstructed the chromosomes of patients with an extremely high number of aberrations in their genome that could alter the expression of nearby genes and potentially cause disease. Their results were published in Nature Communications in October 2022. “We are only beginning to unde more
The architecture of shattered genomes
The Nobel Prize in Physiology or Medicine 2022 goes to Svante Pääbo: What makes us uniquely human?
Humanity has always been intrigued by its origins. Where do we come from, and how are we related to those who came before us? What makes us, Homo sapiens, different from other hominins? Through his pioneering research, Svante Pääbo accomplished something seemingly impossible: sequencing the genome o more
Revealing the Genome of the Common Ancestor of All Mammals
An international team has reconstructed the genome organization of the earliest common ancestor of all mammals. The reconstructed ancestral genome could help in understanding the evolution of mammals and in conservation of modern animals. The earliest mammal ancestor likely looked like the fossil an more