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UPLC® Technology for Performance without Compromises
Increased Resolution, Speed and Sensitivity
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UPLC® Technology, which has been adopted successfully in laboratories around the world for the most demanding separations, is a highly robust, dependable, and reproducible system. What differentiates the system’s holistic design is Waters’ patented sub-2 µm hybrid particle chemistry, significant benefits over today's HPLC systems equipped with standard 5 µm particle chemistries.
The ACQUITY UPLC System, used on its own or paired with Waters optical and MS detection technologies, provides unique end-to-end solutions for all industries
ACQUITY Ultra Performance LC®System Advantages:
Efficiency gains with sub-2 µm particles:
- Provides 3X higher efficiency than 5 µm particles
- 70% higher resolution than 5 µm particles
- For gradient separations, peak capacity is used to measure the resolving power
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Better information gained when analyzing more samples per unit time:
- Column length can be reduced by a factor of three with methods transitioned from 5 µm particles to sub-2 µm particles, with the same efficiency
- Separations can be run at a 3X higher flow rate
- Generate a 9X increase in throughput with no loss in resolution
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Detect compounds at increasingly lower levels without inherent changes to the detection mode, either optical or MS:
- The ACQUITY UPLC® System with sub-2 µm particles provides up to 70% higher sensitivity
- In the case of equal efficiency but faster analysis times, the equivalent is 3X higher sensitivity than 5 µm particles
- Beyond optical detection and looking at MS, the less dispersed peaks with higher concentration effectively yield improved ionization efficiency, making ACQUITY UPLC the ideal inlet for any MS detector
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Additional information
Waters GmbH
Eschborn, Germany
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