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Unique Raman-AFM Microscope Combination for Automated 3-D Chemical Imaging and Surface Inspection WITec introduces the alpha500 and alpha700 series for automated Confocal Raman Imaging and Atomic Force Microscopy

WITec introduces the alpha500 and alpha700 microscopy series for automated Confocal Raman Imaging and Atomic Force Microscopy (AFM) on large samples. The alpha500 and alpha700 are the first instruments on the market to combine Confocal Raman Microscopy for 3-D Chemical Imaging and AFM for high resolution structural imaging in an automated system. Analyzing the samples automatically significantly accelerates the measurement cycles in routine experiments, guaranteeing rapid problem solving and an efficient return on investment. A motorized sample stage with a travel range of 150x100 mm for the alpha500 and 350x300 mm for the alpha700 allows multi-area/multi-point measurements or overview scans on an arbitrary, user-defined number of measurement points. Specific automated functions such as an integrated auto-focus and an automatic AFM-tip approach guarantee that standardized routine measurement procedures or manually defined sequences can be performed without any ongoing process control by an operator. The instruments significantly reduce the overall experiment duration and deliver a greater amount of data in a given time for resource-minimized routine research or high-level quality control, bringing results to market or publication even faster.

Imaging applications involving systematic procedures and routine operations as well as large sample analysis benefit from the new automated design of the alpha500 and alpha700 series. Wafer inspection, pharmaceutical screening, standardized coating and thin film analysis along with forensics or tissue screening are just a few examples of a wide variety of applications.

In the Raman imaging mode, a complete spectrum is acquired in as little as 760 microseconds at each image pixel (Ultrafast Raman Imaging), resulting in images consisting of tens of thousands of Raman spectra being collected in less than a minute. Differences in chemical composition will be apparent in the Raman image and can be analyzed with a spatial resolution down to 200 nm. By simply rotating the objective turret, AFM capabilities are accessible, supporting all standard AFM modes and ensuing high flexibility throughout the full range of AFM applications.