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Delivering on the Promise of the Paperless Lab

11-09-2012

Organizations have made significant investments in enterprise and laboratory tools, technologies and solutions to help improve productivity, better manage data/information and optimize their business processes. However, the reality is that most companies have not reaped the return on investment (ROI) or efficiency gains that they planned. This article demonstrates how the Paperless Lab can...

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Microwave freeze drying of fruits & vegetables

08-08-2012

The concept of microwave freeze drying is based on smaller footprint, higher energy efficiency and better quality in terms of volatiles compared to conventional freeze drying with long vacuum vessels and huge product loads.The application of microwave freeze drying in industrial drying systems is of increasing interest, particularly because of the increasing energy and operational efficiencies...

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From Glass Thermometer to Highly Dynamic Temperature Control Technology

A Juchheim family’s history of success and innovation since 1926

23-07-2012

The first glass thermometers were relatively primitive devices. Equipped with fixed contacts, they were capable of only limited interaction with a relay for things like switching an electric heater on or off or triggering an acoustic warning function. More sophisticated applications required a new development in technology in order to enable variable adjustment of the desired temperature......

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Field-Flow Fractionation - The Universal Separation Principle for Particle and Macromolecule Characterization

22-09-2010

High molecular weight polymers, bio molecules or particles in a range of a few nanometers up to several microns are more and more important in science and technology. Many applications are based on the specific properties of these materials. For this reason, an exact knowledge of the molar mass or particle sizes distribution is essential for later application as well as for optimization of the production processes or quality control. In addition the knowledge about the chain structure of macromolecules or biopolymers as well as about the shape of particles is often necessary. For this reason those samples, which often can be very complex systems, have to be separated according to parameters such as e.g. hydrodynamic volume or molecular weight. After the separation process the resulting narrow dispersed fractions are detected with different techniques....

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New Silicone Technologies for Skin Care

16-11-2009

In today's competitive skin care market, consumers look for a range of benefits, superior aesthetics and cost effectiveness. In response, formulators strive to create products that are multifunctional, easy to use and effective in small quantities. At the same time, the most successful products deliver benefits that stand out from those of the competition. Creams, lotions and color cosmetics must be easy to spread and comfortable to wear, without feeling tacky or greasy. Silicones have been popular ingredients in skin care products for more than fifty years. These versatile materials are known for their emolliency, wetting and spreading characteristics and ability to provide unique aesthetics. As technology continues to evolve, silicones increasingly offer multifunctional, high performance properties. This article reviews some of the newest silicone technologies available for the formulation of innovative skin care products...

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Burn injuries under freezing (labor protection) conditions?

Optimal protection when handling cryogenic liquefied gases

28-10-2009

"A little splash of liquid nitrogen hasn't hurt anybody" - this happens to be a widespread opinion in many laboratories. The real dangers connected to cryogenic gases many people had to learn firsthand, unexpected and painful. Skin irritation, cell and tissue damage or severe burn injuries may occur, depending on the type of contact and exposure time. There are less possibilities of medical treatment than for injuries caused by influence of heat...

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Polyether-Modified Silicones for Cosmetic Applications

20-07-2009

Polyether-modified silicones have a long history of use in the personal care industry as emulsifiers and dispersants, as well as stabilizers for water-in-oil systems. However, because of their external phase type, water-in-oil systems tend to display poor aesthetics, such as greasiness, tackiness and slow absorption. A new polyether-modified silicone, PEG/PPG-19/19 dimethicone (and) C13-16 isoparaffin (and) C10-13 isoparaffin, was evaluated for its potential to aid in the production of stable water-in-silicone and water-in-oil formulations with unique textures and enhanced aesthetics. Various oil phases were studied, including silicone oils, organic oils, and a combination of both. Results of the evaluations demonstrate the versatility of the new material, and prototype formulations illustrate its broad utility...

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Predictor(TM) hERG Fluorescence Polarization Assay Kit performed on the PHERAstar/PHERAstar Plus

28-08-2008

The potential for cardiotoxic side-effects continues to challenge the development of small molecule based therapies. These intolerable side-effects are often precipitated by drug-induced long QT syndrome (LQT), which is often linked to blocking the human ether-a-go-go related gene (hERG) potassium channel. Although patch-clamp electrophysiology remains the gold standard for determining the interaction of compounds with the function of the hERG channel, radioligand displacement assays have proven to be a cost-effective initial alternative assay for hERG channel liability at early stages of compound development....

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"Green Chemstry" in the Laboratory

Using mills as efficient and ecologically friendly synthesis reactors

25-06-2008

The term "green chemistry" is commonly used to describe chemical procedures which meet specific requirements with regards to the conservation of resources and protection of the environment. The objective is to avoid undesired by-products by selecting adequate reaction procedures and media. A typical example is the production of bio fuel which has become an ecologically friendly alternative for many drivers....

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Polyolefins: Determination of Molecular Weight and Branching Structure by GPC/SEC

16-06-2008

Polyethylene and Polypropylene are so-called Polyolefins. They are produced in large amounts every year. Depending on the process and catalyst used linear or branched polymers can be produced. In case of e. g. Polyethylene there are at least three polymer types: HDPE (High Density Polytheylene), LDPE (Low Density Polyethylene) and LLDPE (Linear Low Density Polytehylene). HDPE and LLDPE are made of linear or only slightly branched macromolecules with a high level of crystallinity. They form a dense structure in the final product. LDPE is made of highly branched molecules that form a final structure with low density due to a low degree of crystallinity....

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