Viruses

News Viruses

• Mechanically-driven portable device that extracts nucleic acids from blood to measure HIV viral load

  Research describes the development of a portable device that can extract HIV viral RNA from whole human blood to produce a purified and thermally-stable sample without the use of electric power. The technology has the potential to enable accurate monitoring of patient response to HIV treatment in re more

• Analytik Jena receives major order for diagnostic detection systems from Pakistan

  Analytik Jena AG has received a large order through its Leipzig-based subsidiary AJ Roboscreen GmbH requiring the delivery of systems for the preparation of samples and the detection of various viruses to eleven clinical laboratories in Pakistan. AJ Roboscreen GmbH secured the invitation to tender t more

• Material screening method allows more precise control over stem cells

  When it comes to delivering genes to living human tissue, the odds of success come down the molecule. The entire therapy — including the tools used to bring new genetic material into a cell — must have predictable effects. Now, a new screening process will simplify non-viral transfection, providing more

White papers Viruses

• Superiority of FuGENE® HD Transfection Reagent in Minimizing Non-Specific Cellular Interferon Responses
  

  Many viruses, including human cytomegalovirus (HCMV), encode for genes that can modulate or interfere with the ability of cells to mount an effective antiviral response to infection. Transfection of viral genes into cultures of mammalian cells is an important research tool to evaluate the function of viral gene products. We utilized this approach to identify viral genes involved in modulation of interferon (IFN)-mediated cell signaling pathways. more

• Field-Flow Fractionation - The Universal Separation Principle for Particle and Macromolecule Characterization
  

  High molecular weight polymers, bio molecules or particles in a range of a few nanometers up to several microns are more and more important in science and technology. Many applications are based on the specific properties of these materials. For this reason, an exact knowledge of the molar mass or particle sizes distribution is essential for later application as well as for optimization of the production processes or quality control. In addition the knowledge about the chain structure of macromolecules or biopolymers as well as about the shape of particles is often necessary. For this reason those samples, which often can be very complex systems, have to be separated according to parameters such as e.g. hydrodynamic volume or molecular weight. After the separation process the resulting narrow dispersed fractions are detected with different techniques. more

• Detection of Avian H5N1 Virus with the LightCycler® Instrument
  

  The avian H5N1 influenza virus has killed thousands of birds and caused several fatal cases in humans in Asia and Turkey. A fast and reliable test to identify the virus is urgently required for an effective epedemiological control, and associated medical research activities. RNA viruses mutate easily. Thus, detection has to focus on conserved sequence regions. The preferred gene for the detection of a broad spectrum of influenza A virus variants is the matrix protein (M2) gene. Tests for the specific detection of the H5N1 virus must detect its hemagglutinin (H5) and neuraminidase (N1) genes. more

Websites Viruses